IMMOBILIZED PROTEASE ACTIVITY TESTS FOR DEVELOPING FUNCTIONAL CANCER BIOMARKERS.


Year of Award:
2014
Award Type:
R21
Project Number:
CA174537
RFA Number:
RFA-CA-13-001
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
TEMPST, PAUL
Other PI or Project Leader:
N/A
Institution:
SLOAN-KETTERING INST CAN RESEARCH
The classic path to protein biomarker discovery is by measuring differential levels of proteins in blood or tissues of interest. This approach has not been a great success, mainly because the complexity of the blood proteome precludes detection of protein