SENSOR-SEQ: A GENOME-WIDE BIOLOGICAL MEASURE OF MICRORNA ACTIVITY.


Year of Award:
2013
Award Type:
R33
Project Number:
CA182377
RFA Number:
RFA-CA-13-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
BROWN, BRIAN DAVID
Other PI or Project Leader:
SACHIDANANDAM, RAVI
Institution:
ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
microRNA (miRNA) are a recently uncovered class of regulatory RNAs which help to regulate gene expression, and control cell function. Over 2,000 human miRNAs have been discovered. Many miRNAs have tumor suppressor or oncogenic functions, and miRNA dysregu