NEXT-GENERATION MOUSE GENE-TARGETING TECHNOLOGY TO MODEL TUMORIGENESIS


Year of Award:
2013
Award Type:
R21
Project Number:
CA181859
RFA Number:
RFA-CA-13-001
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
WANG, ZHENGHE
Other PI or Project Leader:
N/A
Institution:
CASE WESTERN RESERVE UNIVERSITY
AbstractThe goal of this application is to develop a very fast and cost-effective method to generate gene-targeted miceto model tumorigenesis. Gene-targeted mice are invaluable tools to determine the roles of oncogenicmutations in cancer development. Howe