KINASE PROFILING WITH QUANTITITATIVE CHEMOPROTEOMICS


Year of Award:
2013
Award Type:
R21
Project Number:
CA177402
RFA Number:
RFA-CA-12-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
ONG, SHAO-EN
Other PI or Project Leader:
MALY, DUSTIN J
Institution:
UNIVERSITY OF WASHINGTON
The long-term goal of this project is to develop a rapid and quantitative method for globally profiling prognostic signaling cascades in tumor cells. Protein kinases are known to participate in larger macromolecular complexes that transmit extra-cellular