CAVITATION ENHANCEMENT OF BIOSPECIMEN PROCESSING FOR IMPROVED DNA FRAGMENTATION


Year of Award:
2012
Award Type:
R21
Project Number:
CA173124
RFA Number:
RFA-CA-12-004
Technology Track:
Biospecimen Science Technologies
PI/Project Leader:
JANZEN, WILLIAM PERRY
Other PI or Project Leader:
DAYTON, PAUL A
Institution:
UNIV OF NORTH CAROLINA CHAPEL HILL
Random, unbiased fragmentation of DNA is necessary for next-generation sequencing (NGS) and chromatin immunoprecipitation (ChIP). Since DNA fragmentation can be a very problematic step for both NGS and ChIP, any technology that increased the efficiency an