ADING COLOR TO CANCER, ADENOVIRUS AND FLOW CYTOMETRY TO IDENTIFY AND CAPTURE CTCS


Year of Award:
2011
Award Type:
R43
Project Number:
CA163436
RFA Number:
RFA-CA-10-013
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
MORACHIS, JOSE MANUEL
Other PI or Project Leader:
BAZHENOVA, LYUDMILA ;O'SHEA, CLODAGH
Institution:
NANOCELLECT BIOMEDICAL, INC.
We propose a novel technique to identify and capture circulating tumor cells (CTCs) using engineered adenoviruses and sophisticated flow cytometry. Current techniques for detection of CTCs include reverse transcriptase-polymerase chain reaction (RT-PCR),