PRUSSIAN BLUE NANOPARTICLES AS CELLULAR T1 MRI CONTRAST AGENTS


Year of Award:
2011
Award Type:
R21
Project Number:
CA143408
RFA Number:
RFA-CA-10-005
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
HUANG, SONGPING D
Other PI or Project Leader:
N/A
Institution:
KENT STATE UNIVERSITY AT KENT
This proposal is aimed at developing Prussian blue nanoparticles (PBNPs) as a new generation of T1-weighted MRI contrast agents (CAs) with high relaxivity, long blood circulation times and ability to penetrate the cell membrane. Prussian blue (PB) is iron