METHODS TO IDENTIFY HIGH-AFFINITY ANTIBODIES THAT TARGET TUMOR-ASSOCIATED GLYCANS


Year of Award:
2011
Award Type:
R21
Project Number:
CA155472
RFA Number:
RFA-CA-10-005
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
LAI, JONATHAN
Other PI or Project Leader:
N/A
Institution:
ALBERT EINSTEIN COLLEGE OF MEDICINE
Monoclonal antibodies are essential reagents for deciphering gene or protein function and have been a fruitful source of therapeutic and diagnostic agents. However, the use of anticarbohydrate antibodies to target glycans for these purposes has been less