DEVELOPMENT OF IMAGING REAGENTS TO MONITOR GTP LEVELS AND GTP/GDP RATIOS IN VIVO


Year of Award:
2010
Award Type:
R21
Project Number:
CA151128
RFA Number:
RFA-CA-09-008
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
SOUSA, RUI J.
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF TEXAS HLTH SCIENCE CENTER
Cellular processes intimately tied to cancer and to a variety of other human pathologies, are globally regulated or coordinated by GTP and ATP, molecules that represent the energy currency of the cell and which are also the most common allosteric modulato