GLOBAL PEPTIDE MICROARRAY PROFILING OF TYROSINE KINASES DEREGULATED IN CANCER


Year of Award:
2010
Award Type:
R21
Project Number:
CA147993
RFA Number:
RFA-CA-09-006
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
TURK, BENJAMIN E
Other PI or Project Leader:
N/A
Institution:
YALE UNIVERSITY
Protein tyrosine kinases (PTKs) play pivotal roles in human cancer and are the targets of a major class of emerging anti-cancer drugs. In a single tumor, multiple PTKs are active and a substantial number are essential for maintaining the transformed pheno