APPLICATION OF 454 SEQUENCING TO CANCER EPIGENOMICS


Year of Award:
2009
Award Type:
R33
Project Number:
CA134304
RFA Number:
RFA-CA-08-008
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
SHI, HUIDONG
Other PI or Project Leader:
N/A
Institution:
GEORGIA REGENTS UNIVERSITY
Although epigenetic components play a major role in driving tumor progression in many human cancers, the methylation landscape in cancer epigenomes is still largely unexplored. Systematic sequence-based methylation analyses are notably absent and as a res