NANOTECHNOLOGY FOR ONE STEP CONCENTRATION AND PRESERVATION OF LABILE BIOMARKERS I


Year of Award:
2009
Award Type:
R21
Project Number:
CA137706
RFA Number:
RFA-CA-08-009
Technology Track:
Biospecimen Science Technologies
PI/Project Leader:
LIOTTA, LANCE ALLEN
Other PI or Project Leader:
N/A
Institution:
GEORGE MASON UNIVERSITY
Cancer-associated blood biomarkers exist in exceedingly low concentrations within complex mixtures of high-abundance proteins such as albumin and immunoglobulins. Moreover, biomarkers in the blood may be subjected to degradation during transportation and