Grants Awarded

Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Yearsort descending Award Type Project # RFA # PI/Project Leader Institution Title Status
2017 R21 RFA-CA-16-001 WONG, WESLEY PHILIP BOSTON CHILDREN'S HOSPITAL Single-molecule mechanical detection of protein and microRNA cancer biomarkers NCE
2017 R21 RFA-CA-16-003 NECHAEV, SERGEI UNIVERSITY OF NORTH DAKOTA Transcriptome profiling of highly degraded specimens through global analysis of short RNA fragments. Active
2017 R33 RFA-CA-16-002 LU, CHANG VIRGINIA POLYTECHNIC INST AND ST UNIV Next-generation MOWChIP-seq for high-throughput epigenomic profiling using clinically relevant samples Complete
2017 R21 RFA-CA-16-001 KARGINOV, ANDREI V UNIVERSITY OF ILLINOIS AT CHICAGO Engineered regulation of tyrosine phosphatase activity in living cells Active
2017 R21 RFA-CA-16-001 DICKINSON, BRYAN UNIVERSITY OF CHICAGO rePPI-i: A system for the rapid continuous evolution of protein-protein interaction inhibitors Active
2017 R33 RFA-CA-16-002 ZENG, YONG UNIVERSITY OF KANSAS LAWRENCE Integrated exosomes profiling for minimally invasive diagnosis and monitoring of cancer NCE
2017 R21 RFA-CA-16-001 BROCK, AMY UNIVERSITY OF TEXAS, AUSTIN High resolution cell lineage tracking and isolation Active
2017 R33 RFA-CA-16-002 LEVENSON, RICHARD M. UNIVERSITY OF CALIFORNIA AT DAVIS Cancer histology and QC via MUSE: Sample-sparing UV surface-excitation microscopy NCE
2018 R21 RFA-CA-17-012 SKARDAL, ALEKSANDER (contact); STROWD, ROY ERVIN WAKE FOREST UNIVERSITY HEALTH SCIENCES Predicting Tumor Heterogeneity Evolution After Therapy In Patient-Derived Ex Vivo Glioblastoma Organoids Active
2018 R21 RFA-CA-17-010 KARGINOV, ANDREI V UNIVERSITY OF ILLINOIS AT CHICAGO Optogenetic tools for the dissection of oncogenic signaling mediated by kinases Active
2018 R33 RFA-CA-17-011 CIMA, MICHAEL J MASSACHUSETTS INSTITUTE OF TECHNOLOGY Advanced development and validation of microdevices for high-throughput in situ drug sensitivity testing in tumors Active
2018 R33 RFA-CA-17-013 BORGES, CHAD R ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Validation and Advanced Development of Albumin Oxidizability as a Marker of Plasma/Serum Integrity Active
2018 R21 RFA-CA-17-010 MAILLOUX, ADAM WILLIAM H. LEE MOFFITT CANCER CTR & RES INST Autohistomagnetic Isolation of Tumor-reactive T-cells Active
2018 R33 RFA-CA-17-011 JIANG, NING UNIVERSITY OF TEXAS, AUSTIN An integrated therapeutic T cell receptor screening platform for adoptive cell therapy in cancer Active
2018 R33 RFA-CA-17-013 INCE, TAN A. UNIVERSITY OF MIAMI SCHOOL OF MEDICINE Live Tumor Culture Core and Tissue Specific Culture (TSC) System for Human Cancers Complete
2018 R21 RFA-CA-17-010 MEHTA, ANAND S MEDICAL UNIVERSITY OF SOUTH CAROLINA Glyco-typer: an antibody capture glycan imaging methodology NCE
2018 R33 RFA-CA-17-011 KONRY, TANIA TALI NORTHEASTERN UNIVERSITY Determining treatment sensitivity in B cell lymphoma by novel microfluidics-based NK cell immunogenicity platform Active
2018 R43 PAR-18-303 LIM, MARK AMBERGEN, INC Highly Multiplexed Nanoscale Mass Spectrometric Imaging of Cancer Tissues Active
2018 R21 RFA-CA-17-010 ROBLES, FRANCISCO E GEORGIA INSTITUTE OF TECHNOLOGY Stimulated Raman scattering spectroscopic optical coherence tomography (SRS-SOCT) for label-free molecular imaging of brain tumor pathology Active
2018 R33 RFA-CA-17-011 LIU, YANG UNIVERSITY OF PITTSBURGH AT PITTSBURGH High-throughput super-resolution imaging of chromatin structures at different epigenetic states Active
2018 R43 PAR-18-303 LEE, LY JAMES NANOMATERIAL INNOVATION, LTD Molecular Beacons in Lipoplex Nanoparticles for Extracellular Vesicles Based Cancer Diagnosis Complete
2018 R21 RFA-CA-17-010 ROYZEN, MAKSIM STATE UNIVERSITY OF NEW YORK AT ALBANY Development of Catch and Release Approach for Multi-Drug Local Delivery of Chemotherapies Active
2018 R33 RFA-CA-17-011 LU, JUN YALE UNIVERSITY CRISPR-based Enhanced Molecular Chipper Technology for Identifying Functional Noncoding Elements in Cancer Active
2018 R43 PAR-18-303 SCHOETTLE, LOUIS GEMNEO BIOSCIENCE, INC. Origami Nanoprobes for Large-Scale Single-Cell Analysis of Lymphocytes Complete
2018 R21 RFA-CA-17-010 SCHIBEL, ANNA ELECTRONIC BIOSCIENCES, INC. Microsatellite Sequencing to Enable Cancer Genotyping Active
2018 R33 RFA-CA-17-011 SALIPANTE, STEPHEN J UNIVERSITY OF WASHINGTON Advanced development and validation of genome-scale molecular diagnostics for microsatelliteinstability using targeted molecular counting methods Active
2018 R21 RFA-CA-17-010 ABBOTT, KAREN L UNIV OF ARKANSAS FOR MED SCIS Novel platform linking cancer-specific glycosylation with cell signaling outcomes Active
2018 R21 RFA-CA-17-010 SHI, TUJIN BATTELLE PACIFIC NORTHWEST LABORATORIES An ultrasensitive targeted mass spectrometry system for proteomics analysis of single cells Active
2018 R33 RFA-CA-17-011 SCHRUM, ADAM G UNIVERSITY OF MISSOURI-COLUMBIA Multiplex matrix ELISA for T cell protein-interaction networks in cancer Active
2018 R21 RFA-CA-17-010 BRENT, ROGER FRED HUTCHINSON CANCER RESEARCH CENTER Precision controllers of mammalian gene expression Active
2018 R21 RFA-CA-17-010 SMITH, LLOYD M UNIVERSITY OF WISCONSIN-MADISON Novel NeuCode Tagging Reagents for Identification and Quantification of Intact Proteoforms in Cancer Tissues Active
2018 R33 RFA-CA-17-011 TEWARI, MUNEESH (contact); WALTER, NILS G UNIVERSITY OF MICHIGAN AT ANN ARBOR Optimization and Validation of Single-Molecule Kinetic Fingerprinting Technology for Rapid, Ultra-Specific Detection of Cancer Mutations Active
2018 R21 RFA-CA-17-010 ENGLER, ADAM JEFFREY UNIVERSITY OF CALIFORNIA, SAN DIEGO Developing Adhesome Technology as a Physical Marker of Highly Metastatic Cells Active
2018 R21 RFA-CA-17-010 VAN DEVENTER, JAMES ALLEN TUFTS UNIVERSITY MEDFORD Discovering hybrid inhibitors for tumor microenvironment disruption Active
2018 R21 RFA-CA-17-012 GULLEY, MARGARET L UNIV OF NORTH CAROLINA CHAPEL HILL EndoGenus Toolkit: A Biometric Method for Absolute Quantification of Tumor Markers by Massive Parallel Sequencing Active
2018 R21 RFA-CA-17-010 FIELDS, RYAN C WASHINGTON UNIVERSITY Advancing Cancer Biology, Diagnostics and Therapeutics Outside of the Patient: Creation of a Novel, Autologous, Ex Vivo, Vascularized Model of the Tumor Microenvironment NCE
2018 R33 RFA-CA-17-011 BROWN, BRIAN D ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Pro-Codes: A novel vector and cell barcoding technology Active
2018 R21 RFA-CA-17-012 PAULOVICH, AMANDA G FRED HUTCHINSON CANCER RESEARCH CENTER Validation of a disposable biospecimen collection system with integral refrigeration for preserving the phosphoproteome NCE
2018 R21 RFA-CA-17-010 FU, XIAO-AN UNIVERSITY OF LOUISVILLE A microreactor chip platform for quantitative analysis of unsaturated aldehydes in exhaled breath Active
2018 R33 RFA-CA-17-011 CHENG, JI-XIN BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) Quantitative SRS Imaging of Cancer Metabolism at Single Cell Level Active
2019 R33 RFA-CA-18-003 DE VLAMINCK, IWIJN CORNELL UNIVERSITY Spatially Resolved Metagenomics to Explore Tumor-Microbiome Interactions in Human Colorectal Cancer Active
2019 R21 RFA-CA-18-002 HUANG, XIAOHUA UNIVERSITY OF CALIFORNIA, SAN DIEGO Technology for measuring telomere length of individual chromosomes of single cancer cells Active
2019 R21 RFA-CA-18-002 ANGEL, PEGGY M MEDICAL UNIVERSITY OF SOUTH CAROLINA Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins Active
2019 R33 RFA-CA-18-003 YANG, JENNY J. GEORGIA STATE UNIVERSITY Multi-color Mapping of Cancer Molecular Signatures and Tumor microenvironment Active
2019 R21 RFA-CA-18-002 WARREN, CHRISTOPHER L PROTEOVISTA, LLC SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants Active
2019 R21 RFA-CA-18-002 KEUNG, ALBERT NORTH CAROLINA STATE UNIVERSITY RALEIGH Intracellular CRISPR gRNA assembly for massively multiplexed; one pot; (epi)genetic screening Active
2019 R33 RFA-CA-18-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Increased Sensitivity of Minimal Residual Disease Monitoring using Peripheral Blood in Pediatric Patients with Acute Lymphoblastic Leukemia Active
2019 R21 RFA-CA-18-002 KENTSIS, ALEX SLOAN-KETTERING INST CAN RESEARCH Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics Active
2019 R21 RFA-CA-18-002 O'NEILL, RACHEL UNIVERSITY OF CONNECTICUT STORRS Development and Utilization of Splice-specific Antibodies Active
2019 R33 RFA-CA-18-003 BREUNIG, JOSHUA JOHN CEDARS-SINAI MEDICAL CENTER GESTALT Barcoding and Single-cell Transcriptomics of Tumor Cell Evolution in Personalized Tumor Models Active