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Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Year Award Type Project #sort ascending RFA # PI/Project Leader Institution Title Status
2020 R33 CA247669 RFA-CA-19-022 HASHAM, MUNEER GULAMHUSEIN JACKSON LABORATORY Impact of Genetic Diversity on Human Xenograft Tumor Growth Active
2020 R44 CA247353 PAR-18-303 FRIEDA, KIRSTEN SPATIAL GENOMICS, INC. Spatial and single cell analysis of tumor microenvironment by seqFISH+ Active
2020 R33 CA246711 RFA-CA-19-020 FAN, RONG YALE UNIVERSITY High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer Active
2020 R21 CA236653 RFA-CA-19-019 ISSADORE, DAVID AARON UNIVERSITY OF PENNSYLVANIA High Throughput Digital Droplet ELISA for Ultrasensitive Multiplexed Diagnostics Active
2020 R33 CA246455 RFA-CA-19-020 CHEN, FEI BROAD INSTITUTE, INC. Clinical implementations of spatial transcriptomics in tumors Active
2020 R21 CA229024 RFA-CA-19-019 HUR, SOOJUNG CLAIRE JOHNS HOPKINS UNIVERSITY Development of a microfluidic primary cell editing platform (pCEP) for personal gene therapy Active
2020 R33 CA246363 RFA-CA-19-020 LEVINSON, NICHOLAS MARK UNIVERSITY OF MINNESOTA Time-resolved FRET-based allostery sensors for any protein kinase drug target Active
2020 R21 CA246359 RFA-CA-19-021 SEIBEL, ERIC J UNIVERSITY OF WASHINGTON Rapid Needle Biopsy Assessment at Point of Care to advance personalized cancer therapy Active
2020 R21 CA246358 RFA-CA-19-019 SEELIG, GEORG UNIVERSITY OF WASHINGTON High-resolution spatial transcriptomics through light patterning Active
2020 R21 CA236612 RFA-CA-19-019 REVZIN, ALEXANDER MAYO CLINIC ROCHESTER A microfluidic cell culture platform for personalizing pancreatic cancer therapies Active
2019 R33 CA235319 RFA-CA-18-003 YANG, JENNY J. GEORGIA STATE UNIVERSITY Multi-color Mapping of Cancer Molecular Signatures and Tumor microenvironment Active
2019 R33 CA229068 RFA-CA-18-003 SCHIAVINATO EBERLIN, LIVIA UNIVERSITY OF TEXAS, AUSTIN Advanced Development of the MasSpec Pen for Cancer Diagnosis and Surgical Margin Evaluation Active
2019 R21 CA240580 RFA-CA-18-002 MONTAGNA, CRISTINA ALBERT EINSTEIN COLLEGE OF MEDICINE Development of a high-resolution mapping platform for HPV DNA integration in premalignant lesions Active
2019 R33 CA235597 RFA-CA-18-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Increased Sensitivity of Minimal Residual Disease Monitoring using Peripheral Blood in Pediatric Patients with Acute Lymphoblastic Leukemia Active
2019 R21 CA240219 RFA-CA-18-004 ANDRES-MARTIN, LAURA NEW YORK STEM CELL FOUNDATION Establishing efficient technologies for ovarian cancer organoid derivation from fresh tumor resections Active
2019 R33 CA240201 RFA-CA-18-003 VAN DAM, ROBERT MICHAEL UNIVERSITY OF CALIFORNIA LOS ANGELES Optimization and validation of integrated microscale technologies for low-cost; automated production of PET molecular imaging tracers for cancer research Active
2019 R21 CA240199 RFA-CA-18-002 O'NEILL, RACHEL UNIVERSITY OF CONNECTICUT STORRS Development and Utilization of Splice-specific Antibodies Active
2019 R33 CA235302 RFA-CA-18-003 DE VLAMINCK, IWIJN CORNELL UNIVERSITY Spatially Resolved Metagenomics to Explore Tumor-Microbiome Interactions in Human Colorectal Cancer Active
2019 R21 CA217662 RFA-CA-18-002 IM, HYUNGSOON MASSACHUSETTS GENERAL HOSPITAL Nano-plasmonic technology for high-throughput single exosome analyses Active
2019 R21 CA240162 RFA-CA-18-002 KEUNG, ALBERT NORTH CAROLINA STATE UNIVERSITY RALEIGH Intracellular CRISPR gRNA assembly for massively multiplexed; one pot; (epi)genetic screening Active
2019 R21 CA240148 RFA-CA-18-002 ANGEL, PEGGY M MEDICAL UNIVERSITY OF SOUTH CAROLINA Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins Active
2019 R43 CA239967 PAR-18-303 BROWN, MARK T CLAREMONT BIOSOLUTIONS, LLC Rapid sample preparation method for high molecular weight DNA from tumor tissues suitable for structural variant analysis Complete
2019 R43 CA236167 PAR-18-303 WARREN, CHRISTOPHER L PROTEOVISTA, LLC Development of the High Throughput APT-SNAP Platform for Rapid Identification ofNuclease-Resistant RNA Aptamers against p53 Missense Mutations NCE
2019 R21 CA236690 RFA-CA-18-002 KIM, HYUN JUNG UNIVERSITY OF TEXAS, AUSTIN A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk Active
2019 R33 CA236687 RFA-CA-18-003 BREUNIG, JOSHUA JOHN CEDARS-SINAI MEDICAL CENTER GESTALT Barcoding and Single-cell Transcriptomics of Tumor Cell Evolution in Personalized Tumor Models Active
2019 R21 CA236685 RFA-CA-18-002 MANALIS, SCOTT R MASSACHUSETTS INSTITUTE OF TECHNOLOGY Building microenvironment-containing organoids from patient samples with single-cell precision Active
2019 R21 CA229069 RFA-CA-18-002 WARREN, CHRISTOPHER L PROTEOVISTA, LLC SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants Active
2019 R21 CA236652 RFA-CA-18-004 SINGAMANENI, SRIKANTH WASHINGTON UNIVERSITY METAL-ORGANIC FRAMEWORK AS PROTECTIVE COATING FOR CANCER BIOSPECIMEN PRESERVATION Active
2019 R33 CA225498 RFA-CA-18-003 CHEN, SIDI YALE UNIVERSITY Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers Active
2019 R21 CA236640 RFA-CA-18-002 BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories for targeting interstitial fluid pressure Active
2019 R33 CA225458 RFA-CA-18-003 KETTENBACH, ARMINJA NADINE DARTMOUTH COLLEGE Activity based profiling of Phosphoprotein phosphatases in cancer using mass spectrometry-based proteomics Active
2019 R33 CA229042 RFA-CA-18-003 SCHNECK, JONATHAN P JOHNS HOPKINS UNIVERSITY A high-throughput nanoparticle assay to characterize cancer neoepitope-specific T cells Active
2019 R21 CA236594 RFA-CA-18-002 GARBER, MANUEL UNIV OF MASSACHUSETTS MED SCH WORCESTER A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells Active
2019 R21 CA236561 RFA-CA-18-002 WEISSLEDER, RALPH MASSACHUSETTS GENERAL HOSPITAL Single Circulating Vesicle Analysis for Early Cancer Detection Active
2018 R43 CA236142 PAR-18-303 SCHOETTLE, LOUIS GEMNEO BIOSCIENCE, INC. Origami Nanoprobes for Large-Scale Single-Cell Analysis of Lymphocytes Complete
2018 R43 CA236097 PAR-18-303 LIM, MARK AMBERGEN, INC Highly Multiplexed Nanoscale Mass Spectrometric Imaging of Cancer Tissues Active
2019 R43 CA236177 PAR-18-303 KASOJI, SANDEEP TRIANGLE BIOTECHNOLOGY, INC. SBIR: Technology for Overcoming Bottlenecks in Chromatin Extraction from Challenging Biological Samples Complete
2018 R43 CA236101 PAR-18-303 LEE, LY JAMES NANOMATERIAL INNOVATION, LTD Molecular Beacons in Lipoplex Nanoparticles for Extracellular Vesicles Based Cancer Diagnosis Complete
2019 R43 CA236103 PAR-18-303 KHODAVERDIAN, VARANDT Y. NUPROBE USA, INC. Allele selective enrichment for targeted profiling of rare cancer mutations via low-depth sequencing Complete
2019 R21 CA235340 RFA-CA-18-002 ZHU, YAZHEN UNIVERSITY OF CALIFORNIA LOS ANGELES Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs Active
2019 R33 CA235326 RFA-CA-18-005 LEI, YUGUO UNIVERSITY OF NEBRASKA LINCOLN A Single Conical Tube Device for Precision CAR-T Cells Manufacturing Active
2019 R21 CA235305 RFA-CA-18-002 WU, YUN STATE UNIVERSITY OF NEW YORK AT BUFFALO Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection Active
2019 R21 CA235303 RFA-CA-18-002 YAMAMOTO, KEITH ROBERT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer Active
2019 R33 CA225549 RFA-CA-18-003 TAVANA, HOSSEIN UNIVERSITY OF AKRON A High Throughput Human Tumor Modeling Technology for Cancer Drug Discovery Active
2019 R21 CA235285 RFA-CA-18-002 KENTSIS, ALEX SLOAN-KETTERING INST CAN RESEARCH Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics Active
2019 R33 CA235254 RFA-CA-18-003 FIOLKA, RETO PAUL UT SOUTHWESTERN MEDICAL CENTER Multiscale microscope for 3D cancer imaging in model organisms and organoids Active
2019 R21 CA223727 RFA-CA-18-002 HUANG, XIAOHUA UNIVERSITY OF CALIFORNIA, SAN DIEGO Technology for measuring telomere length of individual chromosomes of single cancer cells NCE
2020 R43 CA243757 PAR-18-303 ERVIN, ERIC ELECTRONIC BIOSCIENCES, INC. N6-Methyl-2-O-Methyladenosine Sequencing Active
2020 R43 CA250805 PAR-18-303 WANG, SHA VIVID TECHNOLOGIES New specific and rapid assay for in situ apoptosis labeling for cancer studies Active
2020 R33 CA247739 RFA-CA-19-020 MATRIX BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories For Targeting Extracellular Matrix Active

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