Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Yearsort ascending Award Type Project # RFA # PI/Project Leader Institution Title Status
2022 R33 CA21-004 MOELLERING, RAYMOND E UNIVERSITY OF CHICAGO Single-Cell Protein Activity Profiling in Breast Cancer Cells and Tissues Active
2022 R21 RFA-CA-21-003 SALIPANTE, STEPHEN J UNIVERSITY OF WASHINGTON Efficient, cost-effective, and ultrasensitive sequencing of somatic mutations Active
2022 R21 CA21-003 KELLY, RYAN T BRIGHAM YOUNG UNIVERSITY In-depth and label-free proteome profiling of hundreds of single cells per day Active
2022 R33 CA21-004 NORMAN, THOMAS MAXWELL SLOAN-KETTERING INST CAN RESEARCH Systematic characterization of cancer variants using single-cell functional genomics Active
2022 R21 CA21-003 LIN, QIAO COLUMBIA UNIV NEW YORK MORNINGSIDE A Practical Approach to Tumor-Specific Aptamers for B-Cell Hematologic Malignancies Active
2022 R21 RFA-CA-21-003 YAKOVLEV, VLADISLAV V TEXAS ENGINEERING EXPERIMENT STATION Molecular and cellular imaging of bone biopsies using AI augmented deep UV Raman microscopy Active
2022 R21 CA21-005 TANG, SINDY KAM-YAN STANFORD UNIVERSITY A micro-dissection platform for generating uniform-sized patient-derived tumor organoids (PDOs) for personalized cancer therapy Active
2022 R21 CA21-003 LEE, HAKHO MASSACHUSETTS GENERAL HOSPITAL 3D Fourier Imaging System for High Throughput Analyses of Cancer Organoids Active
2022 R21 RFA-CA-21-003 GIBBS, SUMMER LYNNE OREGON HEALTH & SCIENCE UNIVERSITY A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors Active
2022 R21 CA21-003 YAKOVLEV, VLADISLAV V TEXAS ENGINEERING EXPERIMENT STATION Molecular and cellular imaging of bone biopsies using AI augmented deep UV Raman microscopy Active
2022 R21 RFA-CA-21-003 NABA, ALEXANDRA UNIVERSITY OF ILLINOIS AT CHICAGO Enhanced mass-spectrometry-based approaches for in-depth profiling of the cancer extracellular matrix Active
2022 R21 RFA-CA-21-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Molecular Sub-typing Breast Cancer Patients using a Liquid Biopsy Active
2022 R21 CA21-003 KNOWLES, DAVID ARTHUR NEW YORK GENOME CENTER A CRISPR/Cas13 approach for identifying individual transcript isoform function in cancer Active
2022 R21 CA21-003 BELCHER, ANGELA M MASSACHUSETTS INSTITUTE OF TECHNOLOGY A cell-cycle induced genetic recorder for simultaneous recovery of cell divisions and lineage Active
2022 R33 CA21-004 CHIU, BRIAN C-H UNIVERSITY OF CHICAGO A highly sensitive linear amplification based DNA methylation profiling technique for clinical cancer research Active
2022 R33 RFA-CA-21-004 LANDAU, DAN WEILL MEDICAL COLL OF CORNELL UNIV Expanding the GoT toolkit to link single-cell clonal genotypes with protein, transcriptomic, epigenomic and spatial phenotypes Active
2022 R21 CA21-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Molecular Sub-typing Breast Cancer Patients using a Liquid Biopsy Active
2022 R33 CA21-004 DRAKE, RICHARD R MEDICAL UNIVERSITY OF SOUTH CAROLINA Targeted Isolation and Identification of Sialylated Glycoproteins in Cancer Tissues, Cells and Biofluids Active
2022 R21 CA21-003 BLAINEY, PAUL CLARK BROAD INSTITUTE, INC. Stitch-seq for genome-wide pooled genomic screening with RNA-seq readout Active
2021 R21 CA20-017 DEININGER, MICHAEL W VERSITI WISCONSIN, INC. A Bioluminescent Assay for Direct Measurement of Sirtuin Activity in Cancer Cells NCE
2021 R21 RFA-CA-20-017 CHEN, KAI UNIVERSITY OF SOUTHERN CALIFORNIA Novel Bisphosphonate PET Probes for Myeloma Bone Disease Active
2021 R21 CA20-019 NAUTIYAL, SHIVANI PRIME GENOMICS, INC. Device for Preservation of Cell Free RNA in Saliva NCE
2021 R21 CA20-017 SCHULMAN, REBECCA JOHNS HOPKINS UNIVERSITY Secretion responsive Hydrogels for Identification of Functional single T cells (SHIFT) Active
2021 R33 RFA-CA-20-018 JI, HANLEE P STANFORD UNIVERSITY Multimodal iterative sequencing of cancer genomes and single tumor cells Active
2021 R21 CA20-019 AKSAN, ALPTEKIN UNIVERSITY OF MINNESOTA Novel cryopreservation method for stabilization of manufactured therapeutic cells Active
2021 R33 RFA-CA-20-018 GARTNER, ZEV JORDAN UNIVERSITY OF CALIFORNIA, SAN FRANCISCO Universal Sample Multiplexing for Single Cell Analysis Active
2021 R21 CA20-017 BHARGAVA, ROHIT UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN Spectroscopy Assisted Laser Microdissection Active
2021 R33 RFA-CA-20-020 HAUN, JERED BRACKSTON UNIVERSITY OF CALIFORNIA-IRVINE Microfluidic tumor tissue processing platform for single cell diagnostics Active
2021 R33 CA20-018 ZENG, YONG UNIVERSITY OF FLORIDA Integrative Functional Profiling of Tumor-Derived Extracellular Vesicles Active
2021 R21 RFA-CA-20-019 SANTORE, MARIA M UNIVERSITY OF MASSACHUSETTS AMHERST Paper-based Breastmilk Collection System for Facile, In-Home Use Active
2021 R33 RFA-CA-20-018 SEELIG, GEORG UNIVERSITY OF WASHINGTON Joint receptor and protein expression immunophenotyping through split-pool barcoding Active
2021 R33 CA20-018 JIANG, NING JENNY UNIVERSITY OF PENNSYLVANIA A streamlined, high-throughput platform for validation of cancer antigen presentation and isolation of cancer antigen reactive T cells Active
2021 R21 RFA-CA-20-017 WILSON, GERALD M UNIVERSITY OF MARYLAND BALTIMORE Suppressing oncogenic RNA regulons using engineered zinc finger ribonucleases Active
2021 R33 RFA-CA-20-018 GREENBERG, JOEL DUKE UNIVERSITY Multimodality X-ray transmission and diffraction scanner for molecular analysis of cancer specimens Active
2021 R33 CA20-018 WEI, WEI INSTITUTE FOR SYSTEMS BIOLOGY Liquid biopsy-based toolkits for neoantigen and cognate TCR discovery for cancer immunotherapy Active
2021 R21 RFA-CA-20-017 ZHANG, FANGLIANG UNIVERSITY OF MIAMI SCHOOL OF MEDICINE Targeted degradation of proteins by affinity peptide conjugated ubiquitin (APCU) Active
2021 R33 RFA-CA-20-018 HANSEN, ANDERS SEJR MASSACHUSETTS INSTITUTE OF TECHNOLOGY Super-resolution microscopy for dynamic analysis of focal enhancer amplifications in cancer Active
2021 R33 CA20-018 CHENG, JI-XIN BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy Active
2021 R21 RFA-CA-20-017 STILL, AMANDA NICOLE HAYMOND GEORGE MASON UNIVERSITY New Hybrid Molecular Modalities Comprised of DNA-Origami and Interfering Peptides as Inhibitors of Protein-Protein Interactions Active
2021 R43 PAR-18-303 ALLEN, JEFFREY KEITH TUMORGEN, INC. Capture and Characterization of Highly Metastatic Cancer Cell Clusters in Transit from Lung Cancer Patient Whole Blood Specimens. Active
2021 R33 RFA-CA-20-018 LIU, XUEFENG OHIO STATE UNIVERSITY Validating Urine Derived Cancer Cells (UDCC) -- Non-Invasive and Living Liquid Biopsies -- in Bladder Cancer Clinics Active
2021 R21 CA20-017 FARIS, GREGORY W NUMENTUS TECHNOLOGIES INC. Decoding Individual Exosomes in Cancer NCE
2021 R21 RFA-CA-20-017 XIAO, HAN RICE UNIVERSITY Development of Bone-Targeting Antibodies for Ewing Sarcoma Using Genetic Code Expansion Active
2021 R44 PAR-18-303 HUNG, PAUL JU-SUNG COMBINATI, INC. Digital Melt Curve Analysis Platform for Longitudinal Cancer Patient Monitoring Complete
2021 R21 CA20-017 DIDENKO, VLADIMIR V BAYLOR COLLEGE OF MEDICINE In situ assay imaging nuclear RNA exosome activity for cancer studies Active
2021 R21 RFA-CA-20-017 SWAGER, TIMOTHY M MASSACHUSETTS INSTITUTE OF TECHNOLOGY Innovative Droplet Lenses for NextGen Light Sensors of Biomarkers of Inflammation Active
2021 R21 CA20-017 HOSHIKA, SHUICHI FOUNDATION FOR APPLIED MOLECULAR EVOLUTN High Quality Proteins with Multiple Post Translational Modifications Active
2021 R21 CA20-017 HAINER, SARAH JANE UNIVERSITY OF PITTSBURGH AT PITTSBURGH Using nanobodies to increase the sensitivity and resolution of chromatin profiling through uliCUT&RUN Active
2021 R21 RFA-CA-20-017 BAR-PELED, LIRON MASSACHUSETTS GENERAL HOSPITAL Chemical Proteomic Identification of Druggable Oncogenic Transcription Factors Active
2021 R21 CA20-017 DI CARLO, DINO UNIVERSITY OF CALIFORNIA LOS ANGELES Lab on a particle technology for functional screening of therapeutic cells Complete

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