Grants Awarded

Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Year Award Type Project #sort descending RFA # PI/Project Leader Institution Title Status
2018 R43 PAR-18-303 LIM, MARK AMBERGEN, INC Highly Multiplexed Nanoscale Mass Spectrometric Imaging of Cancer Tissues Active
2018 R43 PAR-18-303 SCHOETTLE, LOUIS GEMNEO BIOSCIENCE, INC. Origami Nanoprobes for Large-Scale Single-Cell Analysis of Lymphocytes Complete
2019 R21 RFA-CA-18-002 WEISSLEDER, RALPH MASSACHUSETTS GENERAL HOSPITAL Single Circulating Vesicle Analysis for Early Cancer Detection Active
2019 R21 RFA-CA-18-002 GARBER, MANUEL UNIV OF MASSACHUSETTS MED SCH WORCESTER A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells Active
2019 R33 RFA-CA-18-003 SCHNECK, JONATHAN P JOHNS HOPKINS UNIVERSITY A high-throughput nanoparticle assay to characterize cancer neoepitope-specific T cells Active
2019 R33 RFA-CA-18-003 KETTENBACH, ARMINJA NADINE DARTMOUTH COLLEGE Activity based profiling of Phosphoprotein phosphatases in cancer using mass spectrometry-based proteomics Active
2019 R21 RFA-CA-18-002 BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories for targeting interstitial fluid pressure Active
2019 R33 RFA-CA-18-003 CHEN, SIDI YALE UNIVERSITY Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers Active
2019 R21 RFA-CA-18-002 WARREN, CHRISTOPHER L PROTEOVISTA, LLC SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants Active
2019 R21 RFA-CA-18-002 MANALIS, SCOTT R MASSACHUSETTS INSTITUTE OF TECHNOLOGY Building microenvironment-containing organoids from patient samples with single-cell precision Active
2019 R33 RFA-CA-18-003 BREUNIG, JOSHUA JOHN CEDARS-SINAI MEDICAL CENTER GESTALT Barcoding and Single-cell Transcriptomics of Tumor Cell Evolution in Personalized Tumor Models Active
2019 R21 RFA-CA-18-002 KIM, HYUN JUNG UNIVERSITY OF TEXAS, AUSTIN A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk Active
2019 R43 PAR-18-303 WARREN, CHRISTOPHER L PROTEOVISTA, LLC Development of the High Throughput APT-SNAP Platform for Rapid Identification ofNuclease-Resistant RNA Aptamers against p53 Missense Mutations Active
2019 R43 PAR-18-303 BROWN, MARK T CLAREMONT BIOSOLUTIONS, LLC Rapid sample preparation method for high molecular weight DNA from tumor tissues suitable for structural variant analysis Complete
2019 R21 RFA-CA-18-002 ANGEL, PEGGY M MEDICAL UNIVERSITY OF SOUTH CAROLINA Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins Active
2019 R21 RFA-CA-18-002 KEUNG, ALBERT NORTH CAROLINA STATE UNIVERSITY RALEIGH Intracellular CRISPR gRNA assembly for massively multiplexed; one pot; (epi)genetic screening Active
2019 R21 RFA-CA-18-002 IM, HYUNGSOON MASSACHUSETTS GENERAL HOSPITAL Nano-plasmonic technology for high-throughput single exosome analyses Active
2019 R33 RFA-CA-18-003 DE VLAMINCK, IWIJN CORNELL UNIVERSITY Spatially Resolved Metagenomics to Explore Tumor-Microbiome Interactions in Human Colorectal Cancer Active
2019 R21 RFA-CA-18-002 O'NEILL, RACHEL UNIVERSITY OF CONNECTICUT STORRS Development and Utilization of Splice-specific Antibodies Active
2019 R33 RFA-CA-18-003 VAN DAM, ROBERT MICHAEL UNIVERSITY OF CALIFORNIA LOS ANGELES Optimization and validation of integrated microscale technologies for low-cost; automated production of PET molecular imaging tracers for cancer research Active
2019 R21 RFA-CA-18-004 ANDRES-MARTIN, LAURA NEW YORK STEM CELL FOUNDATION Establishing efficient technologies for ovarian cancer organoid derivation from fresh tumor resections Active
2019 R33 RFA-CA-18-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Increased Sensitivity of Minimal Residual Disease Monitoring using Peripheral Blood in Pediatric Patients with Acute Lymphoblastic Leukemia Active
2019 R21 RFA-CA-18-002 MONTAGNA, CRISTINA ALBERT EINSTEIN COLLEGE OF MEDICINE Development of a high-resolution mapping platform for HPV DNA integration in premalignant lesions Active
2019 R33 RFA-CA-18-003 SCHIAVINATO EBERLIN, LIVIA UNIVERSITY OF TEXAS, AUSTIN Advanced Development of the MasSpec Pen for Cancer Diagnosis and Surgical Margin Evaluation Active
2019 R33 RFA-CA-18-003 YANG, JENNY J. GEORGIA STATE UNIVERSITY Multi-color Mapping of Cancer Molecular Signatures and Tumor microenvironment Active
2020 R21 RFA-CA-19-019 REVZIN, ALEXANDER MAYO CLINIC ROCHESTER A microfluidic cell culture platform for personalizing pancreatic cancer therapies Active
2020 R21 RFA-CA-19-019 SEELIG, GEORG UNIVERSITY OF WASHINGTON High-resolution spatial transcriptomics through light patterning Active
2020 R21 RFA-CA-19-021 SEIBEL, ERIC J UNIVERSITY OF WASHINGTON Rapid Needle Biopsy Assessment at Point of Care to advance personalized cancer therapy Active
2020 R33 RFA-CA-19-020 LEVINSON, NICHOLAS MARK UNIVERSITY OF MINNESOTA Time-resolved FRET-based allostery sensors for any protein kinase drug target Active
2020 R21 RFA-CA-19-019 HUR, SOOJUNG CLAIRE JOHNS HOPKINS UNIVERSITY Development of a microfluidic primary cell editing platform (pCEP) for personal gene therapy Active
2020 R33 RFA-CA-19-020 CHEN, FEI BROAD INSTITUTE, INC. Clinical implementations of spatial transcriptomics in tumors Active
2020 R33 RFA-CA-19-020 TAO, NONGJIAN ARIZONA STATE UNIVERSITY-TEMPE CAMPUS A Virion-Display Oscillator Array and Detection Platform for Quantification of Transmembrane Protein Binding Kinetics Active
2020 R21 RFA-CA-19-019 ISSADORE, DAVID AARON UNIVERSITY OF PENNSYLVANIA High Throughput Digital Droplet ELISA for Ultrasensitive Multiplexed Diagnostics Active
2020 R33 RFA-CA-19-020 FAN, RONG YALE UNIVERSITY High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer Active
2020 R44 PAR-18-303 FRIEDA, KIRSTEN SPATIAL GENOMICS, INC. Spatial and single cell analysis of tumor microenvironment by seqFISH+ Active
2020 R33 RFA-CA-19-022 HASHAM, MUNEER GULAMHUSEIN JACKSON LABORATORY Impact of Genetic Diversity on Human Xenograft Tumor Growth Active
2020 R21 RFA-CA-19-019 MARTO, JARROD A DANA-FARBER CANCER INST Tools for DUB Drug Discovery Active
2020 R33 RFA-CA-19-020 RECHT, MICHAEL PALO ALTO RESEARCH CENTER High-Throughput Screening Platform for Cancer Drug Discovery Active
2020 R33 RFA-CA-19-020 COOKS, ROBERT GRAHAM PURDUE UNIVERSITY Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer using Pathology Biopsies Active
2020 R21 RFA-CA-19-019 CICERONE, MARCUS T GEORGIA INSTITUTE OF TECHNOLOGY Label-Free Cell-Resolved Metabolomics for Tumor Microscopy Active