Grants Awarded
Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.
New awards will be posted as they are issued.
Year |
Award Type | Project # | RFA # | PI/Project Leader | Institution | Title | Status |
|---|---|---|---|---|---|---|---|
| 2016 | R33 | CA196470 | RFA-CA-15-003 | LIN, QIAO | COLUMBIA UNIV NEW YORK MORNINGSIDE | Validating Rapid Microfluidic Isolation of Personalized Aptamers for Monitoring Minimal Residual Disease in Multiple Myeloma | NCE |
| 2016 | R33 | CA202827 | RFA-CA-15-003 | SIMS, PETER ALAN | COLUMBIA UNIVERSITY HEALTH SCIENCES | LARGE-SCALE INTEGRATION OF SINGLE CELL RNA-SEQ AND HIGH-CONTENT IMAGING FOR ANALYZING DRUG RESPONSE IN CANCER | Complete |
| 2016 | R43 | CA203671 | PAR-13-327 | OUELLETTE, STEVEN BRADLEY | KINASENSE, LLC | DEVELOPMENT OF AN ASSAY PLATFORM FOR MEASURING ENDOGENOUS KINASE ACTIVITY | Complete |
| 2016 | R21 | CA193074 | RFA-CA-15-002 | RECHT, MICHAEL | PALO ALTO RESEARCH CENTER | HIGH-THROUGHPUT SCREENING PLATFORM FOR CANCER DRUG DISCOVERY | Complete |
| 2016 | R33 | CA206949 | RFA-CA-15-003 | SPICER, TIMOTHY PATRICK | SCRIPPS FLORIDA | ADVANCED DEVELOPMENT AND VALIDATION OF 3 DIMENSIONAL SPHEROID CULTURE OF PRIMARY CANCER CELLS USING NANO3D TECHNOLOGY | Complete |
| 2016 | R43 | CA203675 | PAR-13-327 | KLUGE, JONATHAN AUGUST | VAXESS TECHNOLOGIES, INC. | SILK-BASED BLOOD SAMPLE STABILIZATION FOR PROSTATE CANCER DIAGNOSTICS | Complete |
| 2016 | R21 | CA186842 | RFA-CA-15-002 | SADEGHI , SAMAN | UNIVERSITY OF CALIFORNIA LOS ANGELES | ELECTROCHEMICAL SYNTHESIS OF RADIOPHARMACEUTICALS | Complete |
| 2016 | R33 | CA202834 | RFA-CA-15-003 | TAO, NONGJIAN | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS | CHARGE SENSITIVE OPTICAL DETECTION FOR HIGH-THROUGHPUT STUDY OF SMALL MOLECULES | Complete |
| 2016 | R43 | CA203629 | PAR-13-327 | GUNDERSON, KEVIN L | ENCODIA, INC. | Development of Reagents for Sequencing Proteins and Protein Fragments on a Next-Generation DNA Sequencer | Complete |
| 2016 | R21 | CA204563 | RFA-CA-15-002 | SEGAL, DAVID J | UNIVERSITY OF CALIFORNIA AT DAVIS | CRISPR-BASED EPIGENETIC MODIFIERS | Complete |
| 2016 | R33 | CA202064 | RFA-CA-15-003 | WEISSLEDER, RALPH | MASSACHUSETTS GENERAL HOSPITAL | ANALYSIS OF SCANT CANCER CELLS IN FINE NEEDLE ASPIRATES | Complete |
| 2016 | R21 | CA204706 | RFA-CA-15-002 | BURGETT, ANTHONY WG | UNIVERSITY OF OKLAHOMA NORMAN | MASS SPECTROMETRY DETECTION OF DRUGS IN SINGLE BLADDER CANCER CELLS FROM PATIENTS | Complete |
| 2016 | R43 | CA203647 | PAR-13-327 | LIM, MARK | AMBERGEN, INC | Photocleavage Technology for Improved Serum-based Multi-Biomarker Cancer Assays | Complete |
| 2016 | R33 | CA196458 | RFA-CA-15-003 | BHARGAVA, ROHIT | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN | TRANSLATIONAL MOLECULAR AND CELLULAR IMAGING TECHNOLOGIES FOR PROSTATE TUMOR PATHOLOGY | Complete |
| 2016 | R21 | CA202849 | RFA-CA-15-004 | GARCIA, ANDRES J | GEORGIA INSTITUTE OF TECHNOLOGY | USHEAR TECHNOLOGY FOR CANCER CELL PURIFICAITON | Complete |
| 2016 | R21 | CA206904 | RFA-CA-15-002 | CHANG, HSUEH-CHIA | UNIVERSITY OF NOTRE DAME | A SOLID-STATE NANOPORE MIRNA QUANTIFICATION TECHNOLOGY | Complete |
| 2016 | R43 | CA203681 | PAR-13-327 | KING, JEFFREY S | VIROGENOMICS BIODEVELOPMENT, INC. | Sensitive Single Cell PhosphoCount Platform for Drug-Insensitive Cell Detection and Combination Drug Screening for Leukemia | Complete |
| 2016 | R33 | CA202900 | RFA-CA-15-003 | BREUNIG, JOSHUA JOHN | CEDARS-SINAI MEDICAL CENTER | A GENETIC TOOLBOX FOR THE IDENTIFICATION AND INTERROGATION OF TUMOR CELLS OF ORIGIN, PROPAGATION, AND RECURRENCE FROM PATIENT-DERIVED ONCOGENIC DRIVERS | Complete |
| 2016 | R21 | CA204707 | RFA-CA-15-004 | JAHNKE, FRANK | SONATA BIOSCIENCES, INC. | A NEW SAMPLE PREPARATION METHOD TO DELVE DEEPER INTO THE PROTEOME | Complete |
| 2016 | R21 | CA202804 | RFA-CA-15-002 | GAMCSIK, MICHAEL | NORTH CAROLINA STATE UNIVERSITY RALEIGH | HIGH-THROUGHPUT SCREENING UNDER STATIC OR DYNAMIC HYPOXIA | NCE |
| 2016 | R44 | CA199194 | PAR-13-327 | KARSTEN, STANISLAV | NEUROINDX INC. | Automated Platform for Fixed Tissue Microdissection | Complete |
| 2017 | R21 | CA212726 | RFA-CA-16-001 | NAEGLE, KRISTEN M | WASHINGTON UNIVERSITY | A MOLECULAR TOOLKIT FOR THE PRODUCTION OF TYROSINE PHOSPHORYLATED PROTEINS | NCE |
| 2017 | R21 | CA214299 | RFA-CA-16-001 | SLATER, JOHN HUNDLEY | UNIVERSITY OF DELAWARE | A Vascularized, In Vitro, Organotropic Metastasis Model to Generate Dormant Micrometastases | NCE |
| 2017 | R33 | CA212968 | RFA-CA-16-002 | SINGH, ANKUR | CORNELL UNIVERSITY | LETSSGo: Lymphoma-on-chip Engineered Technology for Single-Organoid Sequencing and Genomics | Complete |
| 2017 | R21 | CA212731 | RFA-CA-16-001 | DAVIS, RONALD WAYNE | STANFORD UNIVERSITY | Nanoneedle microrobots for single cancer cell manipulation and genome editing | Complete |
| 2017 | R21 | CA217695 | RFA-CA-16-001 | LEVINSON, NICHOLAS MARK | UNIVERSITY OF MINNESOTA | A novel time-resolved fluorescence-based high-throughput screening technology for discovering allosteric kinase inhibitors | Complete |
| 2017 | R33 | CA212973 | RFA-CA-16-002 | YATES, JOHN R | SCRIPPS RESEARCH INSTITUTE | Measurement of Aberrant Protein Folds in Malignant Cells with Proteomics and Mass Spectrometry | Complete |
| 2017 | R21 | CA212827 | RFA-CA-16-001 | WONG, WESLEY PHILIP | BOSTON CHILDREN'S HOSPITAL | Single-molecule mechanical detection of protein and microRNA cancer biomarkers | Complete |
| 2017 | R21 | CA217751 | RFA-CA-16-003 | NECHAEV, SERGEI | UNIVERSITY OF NORTH DAKOTA | Transcriptome profiling of highly degraded specimens through global analysis of short RNA fragments. | NCE |
| 2017 | R33 | CA214176 | RFA-CA-16-002 | LU, CHANG | VIRGINIA POLYTECHNIC INST AND ST UNIV | Next-generation MOWChIP-seq for high-throughput epigenomic profiling using clinically relevant samples | Complete |
| 2017 | R21 | CA212907 | RFA-CA-16-001 | KARGINOV, ANDREI V | UNIVERSITY OF ILLINOIS AT CHICAGO | Engineered regulation of tyrosine phosphatase activity in living cells | NCE |
| 2017 | R21 | CA217754 | RFA-CA-16-001 | DICKINSON, BRYAN | UNIVERSITY OF CHICAGO | rePPI-i: A system for the rapid continuous evolution of protein-protein interaction inhibitors | NCE |
| 2017 | R33 | CA214333 | RFA-CA-16-002 | ZENG, YONG | UNIVERSITY OF KANSAS LAWRENCE | Integrated exosomes profiling for minimally invasive diagnosis and monitoring of cancer | Complete |
| 2017 | R21 | CA212928 | RFA-CA-16-001 | BROCK, AMY | UNIVERSITY OF TEXAS, AUSTIN | High resolution cell lineage tracking and isolation | NCE |
| 2017 | R33 | CA202881 | RFA-CA-16-002 | LEVENSON, RICHARD M. | UNIVERSITY OF CALIFORNIA AT DAVIS | Cancer histology and QC via MUSE: Sample-sparing UV surface-excitation microscopy | Complete |
| 2017 | R33 | CA217652 | RFA-CA-16-002 | MAKRIGIORGOS, G. MIKE | DANA-FARBER CANCER INST | Maximum efficiency sequencing using nuclease-based mutation enrichment and digital barcodes | NCE |
| 2017 | R21 | CA212932 | RFA-CA-16-001 | WONG, IAN Y | BROWN UNIVERSITY | High Content Screening of Multicellular Invasion with 3D Traction Force Microscopy | Complete |
| 2017 | R33 | CA204574 | RFA-CA-16-002 | KELLEY, SHANA O | UNIVERSITY OF TORONTO | Development and validation of nanoparticle-mediated microfluidic profiling approach for rare cell analysis | Complete |
| 2017 | R33 | CA217699 | RFA-CA-16-002 | IBRAHIM, YEHIA | BATTELLE PACIFIC NORTHWEST LABORATORIES | High Resolution High Throughput Proteomics Platform for Cancer Research | NCE |
| 2017 | R21 | CA204560 | RFA-CA-16-001 | WALTER, NILS G | UNIVERSITY OF MICHIGAN AT ANN ARBOR | Single-molecule counting of cancer biomarker miRNAs in human biofluids | Complete |
| 2017 | R21 | CA212958 | RFA-CA-16-001 | KESHARI, KAYVAN R. | SLOAN-KETTERING INST CAN RESEARCH | uCoil NMR platform for robust and high-throughput analysis of in vitro metabolic flux on living cells | Complete |
| 2017 | R33 | CA204704 | RFA-CA-16-002 | WANG, YINGXIAO | UNIVERSITY OF CALIFORNIA, SAN DIEGO | Multiplex FRET Imaging of Kinase-Epigenome Interregulations in Live Cancer Cells | Complete |
| 2017 | R33 | CA217700 | RFA-CA-16-002 | WALTER, MATTHEW J | WASHINGTON UNIVERSITY | TARGETED SINGLE-MOLECULE SEQUENCING ASSAY INCORPORATING MOLECULAR BARCODES | NCE |
| 2017 | R21 | CA204708 | RFA-CA-16-001 | MALMSTADT, NOAH | UNIVERSITY OF SOUTHERN CALIFORNIA | A Target-Directed Reagent Pipeline via Microfluidic mRNA Display | Complete |
| 2017 | R21 | CA212967 | RFA-CA-16-001 | WINDLE, BRAD E. | VIRGINIA COMMONWEALTH UNIVERSITY | The GOF Mutant p53 Beacon System | Complete |
| 2017 | R33 | CA206907 | RFA-CA-16-004 | ISSADORE, DAVID AARON | UNIVERSITY OF PENNSYLVANIA | Rapid unbiased isolation and in situ RNA analysis of circulating tumor cells using a magnetic micropore-based diagnostic chip | NCE |
| 2017 | R33 | CA217780 | RFA-CA-16-002 | PARKER, LAURIE L. | UNIVERSITY OF MINNESOTA | Fluorescence lifetime-based single fluorophore biosensors of post-translational modification enzyme activity | NCE |
| 2017 | R21 | CA212495 | RFA-CA-16-001 | EASWARAN, HARIHARAN | JOHNS HOPKINS UNIVERSITY | High-efficiency microfluidic-assisted single-cell DNA methylome sequencing | NCE |
| 2017 | R21 | CA213234 | RFA-CA-16-003 | WELJIE, AALIM M | UNIVERSITY OF PENNSYLVANIA | Determining and enhancing metabolite fitness for metabolomics measurements | Complete |
| 2017 | R33 | CA206939 | RFA-CA-16-004 | PATTENDEN, SAMANTHA GAIL | UNIV OF NORTH CAROLINA CHAPEL HILL | The application of Enhanced Cavitation to enable DNA and Chromatin Extraction from Archived Tissues | NCE |