Grants Awarded

Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Yearsort ascending Award Type Project # RFA # PI/Project Leader Institution Title Status
2020 R33 RFA-CA-19-020 CHEN, FEI BROAD INSTITUTE, INC. Clinical implementations of spatial transcriptomics in tumors Active
2019 R33 RFA-CA-18-003 TAVANA, HOSSEIN UNIVERSITY OF AKRON A High Throughput Human Tumor Modeling Technology for Cancer Drug Discovery Active
2019 R33 RFA-CA-18-005 LEI, YUGUO UNIVERSITY OF NEBRASKA LINCOLN A Single Conical Tube Device for Precision CAR-T Cells Manufacturing Active
2019 R43 PAR-18-303 WARREN, CHRISTOPHER L PROTEOVISTA, LLC Development of the High Throughput APT-SNAP Platform for Rapid Identification ofNuclease-Resistant RNA Aptamers against p53 Missense Mutations NCE
2019 R21 RFA-CA-18-002 GARBER, MANUEL UNIV OF MASSACHUSETTS MED SCH WORCESTER A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells Active
2019 R33 RFA-CA-18-003 SCHNECK, JONATHAN P JOHNS HOPKINS UNIVERSITY A high-throughput nanoparticle assay to characterize cancer neoepitope-specific T cells Active
2019 R43 PAR-18-303 KASOJI, SANDEEP TRIANGLE BIOTECHNOLOGY, INC. SBIR: Technology for Overcoming Bottlenecks in Chromatin Extraction from Challenging Biological Samples Complete
2019 R21 RFA-CA-18-002 BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories for targeting interstitial fluid pressure Active
2019 R33 RFA-CA-18-003 SCHIAVINATO EBERLIN, LIVIA UNIVERSITY OF TEXAS, AUSTIN Advanced Development of the MasSpec Pen for Cancer Diagnosis and Surgical Margin Evaluation Active
2019 R43 PAR-18-303 BROWN, MARK T CLAREMONT BIOSOLUTIONS, LLC Rapid sample preparation method for high molecular weight DNA from tumor tissues suitable for structural variant analysis Complete
2019 R21 RFA-CA-18-002 MANALIS, SCOTT R MASSACHUSETTS INSTITUTE OF TECHNOLOGY Building microenvironment-containing organoids from patient samples with single-cell precision Active
2019 R33 RFA-CA-18-003 FIOLKA, RETO PAUL UT SOUTHWESTERN MEDICAL CENTER Multiscale microscope for 3D cancer imaging in model organisms and organoids Active
2019 R21 RFA-CA-18-002 IM, HYUNGSOON MASSACHUSETTS GENERAL HOSPITAL Nano-plasmonic technology for high-throughput single exosome analyses Active
2019 R21 RFA-CA-18-002 KIM, HYUN JUNG UNIVERSITY OF TEXAS, AUSTIN A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk Active
2019 R33 RFA-CA-18-003 DE VLAMINCK, IWIJN CORNELL UNIVERSITY Spatially Resolved Metagenomics to Explore Tumor-Microbiome Interactions in Human Colorectal Cancer Active
2019 R21 RFA-CA-18-002 HUANG, XIAOHUA UNIVERSITY OF CALIFORNIA, SAN DIEGO Technology for measuring telomere length of individual chromosomes of single cancer cells NCE
2019 R21 RFA-CA-18-002 ANGEL, PEGGY M MEDICAL UNIVERSITY OF SOUTH CAROLINA Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins Active
2019 R33 RFA-CA-18-003 YANG, JENNY J. GEORGIA STATE UNIVERSITY Multi-color Mapping of Cancer Molecular Signatures and Tumor microenvironment Active
2019 R21 RFA-CA-18-002 WARREN, CHRISTOPHER L PROTEOVISTA, LLC SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants Active
2019 R21 RFA-CA-18-002 KEUNG, ALBERT NORTH CAROLINA STATE UNIVERSITY RALEIGH Intracellular CRISPR gRNA assembly for massively multiplexed; one pot; (epi)genetic screening Active
2019 R33 RFA-CA-18-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Increased Sensitivity of Minimal Residual Disease Monitoring using Peripheral Blood in Pediatric Patients with Acute Lymphoblastic Leukemia Active
2019 R21 RFA-CA-18-002 KENTSIS, ALEX SLOAN-KETTERING INST CAN RESEARCH Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics Active
2019 R21 RFA-CA-18-002 O'NEILL, RACHEL UNIVERSITY OF CONNECTICUT STORRS Development and Utilization of Splice-specific Antibodies Active
2019 R33 RFA-CA-18-003 BREUNIG, JOSHUA JOHN CEDARS-SINAI MEDICAL CENTER GESTALT Barcoding and Single-cell Transcriptomics of Tumor Cell Evolution in Personalized Tumor Models Active
2019 R21 RFA-CA-18-002 YAMAMOTO, KEITH ROBERT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer Active
2019 R21 RFA-CA-18-002 MONTAGNA, CRISTINA ALBERT EINSTEIN COLLEGE OF MEDICINE Development of a high-resolution mapping platform for HPV DNA integration in premalignant lesions Active
2019 R33 RFA-CA-18-003 VAN DAM, ROBERT MICHAEL UNIVERSITY OF CALIFORNIA LOS ANGELES Optimization and validation of integrated microscale technologies for low-cost; automated production of PET molecular imaging tracers for cancer research Active
2019 R21 RFA-CA-18-002 WU, YUN STATE UNIVERSITY OF NEW YORK AT BUFFALO Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection Active
2019 R33 RFA-CA-18-003 KETTENBACH, ARMINJA NADINE DARTMOUTH COLLEGE Activity based profiling of Phosphoprotein phosphatases in cancer using mass spectrometry-based proteomics Active
2019 R21 RFA-CA-18-002 ZHU, YAZHEN UNIVERSITY OF CALIFORNIA LOS ANGELES Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs Active
2019 R33 RFA-CA-18-003 CHEN, SIDI YALE UNIVERSITY Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers Active
2019 R21 RFA-CA-18-004 ANDRES-MARTIN, LAURA NEW YORK STEM CELL FOUNDATION Establishing efficient technologies for ovarian cancer organoid derivation from fresh tumor resections Active
2019 R43 PAR-18-303 KHODAVERDIAN, VARANDT Y. NUPROBE USA, INC. Allele selective enrichment for targeted profiling of rare cancer mutations via low-depth sequencing Complete
2019 R21 RFA-CA-18-002 WEISSLEDER, RALPH MASSACHUSETTS GENERAL HOSPITAL Single Circulating Vesicle Analysis for Early Cancer Detection Active
2018 R33 RFA-CA-17-011 SCHRUM, ADAM G UNIVERSITY OF MISSOURI-COLUMBIA Multiplex matrix ELISA for T cell protein-interaction networks in cancer Active
2018 R21 RFA-CA-17-010 BRENT, ROGER FRED HUTCHINSON CANCER RESEARCH CENTER Precision controllers of mammalian gene expression Active
2018 R21 RFA-CA-17-010 SMITH, LLOYD M UNIVERSITY OF WISCONSIN-MADISON Novel NeuCode Tagging Reagents for Identification and Quantification of Intact Proteoforms in Cancer Tissues NCE
2018 R33 RFA-CA-17-011 TEWARI, MUNEESH (contact); WALTER, NILS G UNIVERSITY OF MICHIGAN AT ANN ARBOR Optimization and Validation of Single-Molecule Kinetic Fingerprinting Technology for Rapid, Ultra-Specific Detection of Cancer Mutations Active
2018 R21 RFA-CA-17-010 ENGLER, ADAM JEFFREY UNIVERSITY OF CALIFORNIA, SAN DIEGO Developing Adhesome Technology as a Physical Marker of Highly Metastatic Cells Complete
2018 R21 RFA-CA-17-010 VAN DEVENTER, JAMES ALLEN TUFTS UNIVERSITY MEDFORD Discovering hybrid inhibitors for tumor microenvironment disruption NCE
2018 R21 RFA-CA-17-012 GULLEY, MARGARET L UNIV OF NORTH CAROLINA CHAPEL HILL EndoGenus Toolkit: A Biometric Method for Absolute Quantification of Tumor Markers by Massive Parallel Sequencing Active
2018 R21 RFA-CA-17-010 FIELDS, RYAN C WASHINGTON UNIVERSITY Advancing Cancer Biology, Diagnostics and Therapeutics Outside of the Patient: Creation of a Novel, Autologous, Ex Vivo, Vascularized Model of the Tumor Microenvironment NCE
2018 R33 RFA-CA-17-011 BROWN, BRIAN D ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Pro-Codes: A novel vector and cell barcoding technology Active
2018 R21 RFA-CA-17-012 PAULOVICH, AMANDA G FRED HUTCHINSON CANCER RESEARCH CENTER Validation of a disposable biospecimen collection system with integral refrigeration for preserving the phosphoproteome NCE
2018 R21 RFA-CA-17-010 FU, XIAO-AN UNIVERSITY OF LOUISVILLE A microreactor chip platform for quantitative analysis of unsaturated aldehydes in exhaled breath Active
2018 R33 RFA-CA-17-011 CHENG, JI-XIN BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) Quantitative SRS Imaging of Cancer Metabolism at Single Cell Level Active
2018 R21 RFA-CA-17-012 SKARDAL, ALEKSANDER (contact); STROWD, ROY ERVIN WAKE FOREST UNIVERSITY HEALTH SCIENCES Predicting Tumor Heterogeneity Evolution After Therapy In Patient-Derived Ex Vivo Glioblastoma Organoids Complete
2018 R21 RFA-CA-17-010 KARGINOV, ANDREI V UNIVERSITY OF ILLINOIS AT CHICAGO Optogenetic tools for the dissection of oncogenic signaling mediated by kinases NCE
2018 R33 RFA-CA-17-011 CIMA, MICHAEL J MASSACHUSETTS INSTITUTE OF TECHNOLOGY Advanced development and validation of microdevices for high-throughput in situ drug sensitivity testing in tumors NCE