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Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Year Award Type Project #sort descending RFA # PI/Project Leader Institution Title Status
2018 R33 CA225539 RFA-CA-17-011 JIANG, NING UNIVERSITY OF TEXAS, AUSTIN An integrated therapeutic T cell receptor screening platform for adoptive cell therapy in cancer Active
2018 R21 CA217735 RFA-CA-17-010 ENGLER, ADAM JEFFREY UNIVERSITY OF CALIFORNIA, SAN DIEGO Developing Adhesome Technology as a Physical Marker of Highly Metastatic Cells Complete
2018 R33 CA225863 RFA-CA-17-011 LU, JUN YALE UNIVERSITY CRISPR-based Enhanced Molecular Chipper Technology for Identifying Functional Noncoding Elements in Cancer NCE
2018 R33 CA223581 RFA-CA-17-011 CHENG, JI-XIN BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) Quantitative SRS Imaging of Cancer Metabolism at Single Cell Level Active
2018 R21 CA228948 RFA-CA-17-010 SCHIBEL, ANNA ELECTRONIC BIOSCIENCES, INC. Microsatellite Sequencing to Enable Cancer Genotyping NCE
2018 R33 CA228979 RFA-CA-17-011 SCHRUM, ADAM G UNIVERSITY OF MISSOURI-COLUMBIA Multiplex matrix ELISA for T cell protein-interaction networks in cancer Active
2018 R33 CA217702 RFA-CA-17-013 BORGES, CHAD R ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Validation and Advanced Development of Albumin Oxidizability as a Marker of Plasma/Serum Integrity Active
2018 R21 CA228997 RFA-CA-17-010 ROYZEN, MAKSIM STATE UNIVERSITY OF NEW YORK AT ALBANY Development of Catch and Release Approach for Multi-Drug Local Delivery of Chemotherapies Active
2018 R33 CA229023 RFA-CA-17-011 TEWARI, MUNEESH (contact); WALTER, NILS G UNIVERSITY OF MICHIGAN AT ANN ARBOR Optimization and Validation of Single-Molecule Kinetic Fingerprinting Technology for Rapid, Ultra-Specific Detection of Cancer Mutations Active
2018 R33 CA223947 RFA-CA-17-011 BROWN, BRIAN D ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Pro-Codes: A novel vector and cell barcoding technology Active
2018 R21 CA229027 RFA-CA-17-012 SKARDAL, ALEKSANDER (contact); STROWD, ROY ERVIN WAKE FOREST UNIVERSITY HEALTH SCIENCES Predicting Tumor Heterogeneity Evolution After Therapy In Patient-Derived Ex Vivo Glioblastoma Organoids Complete
2018 R21 CA229037 RFA-CA-17-012 GULLEY, MARGARET L UNIV OF NORTH CAROLINA CHAPEL HILL EndoGenus Toolkit: A Biometric Method for Absolute Quantification of Tumor Markers by Massive Parallel Sequencing Active
2018 R21 CA229044 RFA-CA-17-010 ABBOTT, KAREN L UNIV OF ARKANSAS FOR MED SCIS Novel platform linking cancer-specific glycosylation with cell signaling outcomes Active
2018 R21 CA229057 RFA-CA-17-010 FU, XIAO-AN UNIVERSITY OF LOUISVILLE A microreactor chip platform for quantitative analysis of unsaturated aldehydes in exhaled breath Active
2018 R21 CA214285 RFA-CA-17-010 MAILLOUX, ADAM WILLIAM H. LEE MOFFITT CANCER CTR & RES INST Autohistomagnetic Isolation of Tumor-reactive T-cells Complete
2020 R43 CA236167 PAR-18-303 WARREN, CHRISTOPHER L PROTEOVISTA, LLC Development Of The High Throughput Apt-snap Platform For Rapid Identification Ofnuclease-resistant Rna Aptamers Against P53 Missense Mutations Active
2020 R33 CA236681 RFA-CA-19-020 WEI, CHIA-LIN JACKSON LABORATORY Advancing Ultra Long-read Sequencing And Chromatin Interaction Analyses For Chromosomal And Extrachromosomal Structural Variation Characterization In Cancer Active
2020 R33 CA236670 RFA-CA-19-020 HIGGINSON, DANIEL SLOAN-KETTERING INST CAN RESEARCH Comprehensive Breakpoint Analyses For Simultaneous Quantification Of All Dna Double Strand Break Repair Pathways Active
2020 R21 CA247638 RFA-CA-19-019 LIANG, FU-SEN CASE WESTERN RESERVE UNIVERSITY Spatiotemporal Epitranscriptome Editing Technology Active
2020 R21 CA240220 RFA-CA-19-019 ALEXANDRAKIS, GEORGIOS UNIVERSITY OF TEXAS ARLINGTON Nanotechnology Enabled Selection Of MHC-peptide Ligands To Personalize Cancer Therapy Active
2020 R33 CA240181 RFA-CA-19-020 COOKS, ROBERT GRAHAM PURDUE UNIVERSITY Advanced Development Of Desorption Electrospray Ionization Mass Spectrometry For Intraoperative Molecular Diagnosis Of Brain Cancer Using Pathology Biopsies Active
2020 R33 CA247739 RFA-CA-19-020 MATRIX BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories For Targeting Extracellular Matrix Active
2020 R43 CA250805 PAR-18-303 WANG, SHA VIVID TECHNOLOGIES New specific and rapid assay for in situ apoptosis labeling for cancer studies Active
2020 R43 CA243757 PAR-18-303 ERVIN, ERIC ELECTRONIC BIOSCIENCES, INC. N6-Methyl-2-O-Methyladenosine Sequencing Active
2019 R21 CA223727 RFA-CA-18-002 HUANG, XIAOHUA UNIVERSITY OF CALIFORNIA, SAN DIEGO Technology for measuring telomere length of individual chromosomes of single cancer cells NCE
2019 R33 CA235254 RFA-CA-18-003 FIOLKA, RETO PAUL UT SOUTHWESTERN MEDICAL CENTER Multiscale microscope for 3D cancer imaging in model organisms and organoids Active
2019 R21 CA235285 RFA-CA-18-002 KENTSIS, ALEX SLOAN-KETTERING INST CAN RESEARCH Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics Active
2019 R33 CA225549 RFA-CA-18-003 TAVANA, HOSSEIN UNIVERSITY OF AKRON A High Throughput Human Tumor Modeling Technology for Cancer Drug Discovery Active
2019 R21 CA235303 RFA-CA-18-002 YAMAMOTO, KEITH ROBERT UNIVERSITY OF CALIFORNIA, SAN FRANCISCO CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer Active
2019 R21 CA235305 RFA-CA-18-002 WU, YUN STATE UNIVERSITY OF NEW YORK AT BUFFALO Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection Active
2019 R33 CA235326 RFA-CA-18-005 LEI, YUGUO UNIVERSITY OF NEBRASKA LINCOLN A Single Conical Tube Device for Precision CAR-T Cells Manufacturing Active
2019 R21 CA235340 RFA-CA-18-002 ZHU, YAZHEN UNIVERSITY OF CALIFORNIA LOS ANGELES Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs Active
2019 R43 CA236103 PAR-18-303 KHODAVERDIAN, VARANDT Y. NUPROBE USA, INC. Allele selective enrichment for targeted profiling of rare cancer mutations via low-depth sequencing Complete
2018 R43 CA236101 PAR-18-303 LEE, LY JAMES NANOMATERIAL INNOVATION, LTD Molecular Beacons in Lipoplex Nanoparticles for Extracellular Vesicles Based Cancer Diagnosis Complete
2019 R43 CA236177 PAR-18-303 KASOJI, SANDEEP TRIANGLE BIOTECHNOLOGY, INC. SBIR: Technology for Overcoming Bottlenecks in Chromatin Extraction from Challenging Biological Samples Complete
2018 R43 CA236097 PAR-18-303 LIM, MARK AMBERGEN, INC Highly Multiplexed Nanoscale Mass Spectrometric Imaging of Cancer Tissues Active
2018 R43 CA236142 PAR-18-303 SCHOETTLE, LOUIS GEMNEO BIOSCIENCE, INC. Origami Nanoprobes for Large-Scale Single-Cell Analysis of Lymphocytes Complete
2019 R21 CA236561 RFA-CA-18-002 WEISSLEDER, RALPH MASSACHUSETTS GENERAL HOSPITAL Single Circulating Vesicle Analysis for Early Cancer Detection Active
2019 R21 CA236594 RFA-CA-18-002 GARBER, MANUEL UNIV OF MASSACHUSETTS MED SCH WORCESTER A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells Active
2019 R33 CA229042 RFA-CA-18-003 SCHNECK, JONATHAN P JOHNS HOPKINS UNIVERSITY A high-throughput nanoparticle assay to characterize cancer neoepitope-specific T cells Active
2019 R33 CA225458 RFA-CA-18-003 KETTENBACH, ARMINJA NADINE DARTMOUTH COLLEGE Activity based profiling of Phosphoprotein phosphatases in cancer using mass spectrometry-based proteomics Active
2019 R21 CA236640 RFA-CA-18-002 BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories for targeting interstitial fluid pressure Active
2019 R33 CA225498 RFA-CA-18-003 CHEN, SIDI YALE UNIVERSITY Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers Active
2019 R21 CA236652 RFA-CA-18-004 SINGAMANENI, SRIKANTH WASHINGTON UNIVERSITY METAL-ORGANIC FRAMEWORK AS PROTECTIVE COATING FOR CANCER BIOSPECIMEN PRESERVATION Active
2019 R21 CA229069 RFA-CA-18-002 WARREN, CHRISTOPHER L PROTEOVISTA, LLC SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants Active
2019 R21 CA236685 RFA-CA-18-002 MANALIS, SCOTT R MASSACHUSETTS INSTITUTE OF TECHNOLOGY Building microenvironment-containing organoids from patient samples with single-cell precision Active
2019 R33 CA236687 RFA-CA-18-003 BREUNIG, JOSHUA JOHN CEDARS-SINAI MEDICAL CENTER GESTALT Barcoding and Single-cell Transcriptomics of Tumor Cell Evolution in Personalized Tumor Models Active
2019 R21 CA236690 RFA-CA-18-002 KIM, HYUN JUNG UNIVERSITY OF TEXAS, AUSTIN A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk Active
2019 R43 CA236167 PAR-18-303 WARREN, CHRISTOPHER L PROTEOVISTA, LLC Development of the High Throughput APT-SNAP Platform for Rapid Identification ofNuclease-Resistant RNA Aptamers against p53 Missense Mutations NCE
2019 R43 CA239967 PAR-18-303 BROWN, MARK T CLAREMONT BIOSOLUTIONS, LLC Rapid sample preparation method for high molecular weight DNA from tumor tissues suitable for structural variant analysis Complete

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