Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Yearsort descending Award Type Project # RFA # PI/Project Leader Institution Title Status
2022 R21 RFA-CA-21-003 KNOWLES, DAVID ARTHUR NEW YORK GENOME CENTER A CRISPR/Cas13 approach for identifying individual transcript isoform function in cancer Active
2022 R33 CA21-004 MERAJVER, SOFIA DIANA UNIVERSITY OF MICHIGAN AT ANN ARBOR Advanced development and validation of an in vitro platform to phenotype brain metastatic tumor cells using artificial intelligence Active
2022 R21 CA21-005 SHIBATA, DARRYL K UNIVERSITY OF SOUTHERN CALIFORNIA Photolithographic Tumor DNA Isolation Active
2022 R21 CA21-003 GIBBS, SUMMER LYNNE OREGON HEALTH & SCIENCE UNIVERSITY A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors Active
2022 R33 CA21-004 ADEY, ANDREW OREGON HEALTH & SCIENCE UNIVERSITY Accessible high-throughput single-cell genome sequencing Active
2022 R33 CA21-004 LANDAU, DAN WEILL MEDICAL COLL OF CORNELL UNIV Expanding the GoT toolkit to link single-cell clonal genotypes with protein, transcriptomic, epigenomic and spatial phenotypes Active
2022 R21 CA21-005 BORGES, CHAD R ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Aliquot-level visual indicators of biospecimen exposure to thawed conditions Complete
2022 R33 CA21-004 KARGINOV, ANDREI V UNIVERSITY OF ILLINOIS AT CHICAGO Optogenetic Control of Tumor Initiation and Tumor Progression in vivo Active
2022 R33 CA21-004 WANG, TZA-HUEI JEFF JOHNS HOPKINS UNIVERSITY A low-cost, multiplexed digital high resolution melt platform for DNA methylation-based detection and identification of cancers in liquid biopsies Active
2022 R21 CA21-003 BOYLE, ALAN P UNIVERSITY OF MICHIGAN AT ANN ARBOR High-throughput inverted reporter assay for characterization of silencers and enhancer blockers Complete
2022 R33 RFA-CA-21-004 WANG, TZA-HUEI JEFF JOHNS HOPKINS UNIVERSITY A low-cost, multiplexed digital high resolution melt platform for DNA methylation-based detection and identification of cancers in liquid biopsies Active
2022 R33 RFA-CA-21-004 PAN, TAO UNIVERSITY OF CHICAGO Transfer RNA sequencing and application to cancer research and clinics Active
2022 R21 CA21-005 BORGES, CHAD R ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Plate reader assays to forensically assess exposure of plasma and serum to thawed conditions Active
2022 R33 CA21-004 NAEGLE, KRISTEN M UNIVERSITY OF VIRGINIA A synthetic toolkit for the recombinant production of tyrosine phosphorylated proteins and peptides Active
2022 R33 RFA-CA-21-004 LEE, ABRAHAM P UNIVERSITY OF CALIFORNIA-IRVINE Microfluidic Precision Engineered Artificial Antigen Presenting Cells for Cancer Immunotherapy Active
2022 R21 CA21-003 SCARCELLI, GIULIANO UNIV OF MARYLAND, COLLEGE PARK Stimulated Brillouin Flow Cytometry for biomechanical assessment of metastatic potential Complete
2022 R21 RFA-CA-21-005 TANG, SINDY KAM-YAN STANFORD UNIVERSITY A micro-dissection platform for generating uniform-sized patient-derived tumor organoids (PDOs) for personalized cancer therapy Active
2022 R33 CA21-004 MOELLERING, RAYMOND E UNIVERSITY OF CHICAGO Single-Cell Protein Activity Profiling in Breast Cancer Cells and Tissues Active
2022 R21 RFA-CA-21-003 SALIPANTE, STEPHEN J UNIVERSITY OF WASHINGTON Efficient, cost-effective, and ultrasensitive sequencing of somatic mutations Active
2022 R21 CA21-003 KELLY, RYAN T BRIGHAM YOUNG UNIVERSITY In-depth and label-free proteome profiling of hundreds of single cells per day Active
2022 R33 CA21-004 NORMAN, THOMAS MAXWELL SLOAN-KETTERING INST CAN RESEARCH Systematic characterization of cancer variants using single-cell functional genomics Active
2022 R21 CA21-003 LIN, QIAO COLUMBIA UNIV NEW YORK MORNINGSIDE A Practical Approach to Tumor-Specific Aptamers for B-Cell Hematologic Malignancies Active
2022 R21 CA21-005 TANG, SINDY KAM-YAN STANFORD UNIVERSITY A micro-dissection platform for generating uniform-sized patient-derived tumor organoids (PDOs) for personalized cancer therapy Active
2022 R21 RFA-CA-21-003 YAKOVLEV, VLADISLAV V TEXAS ENGINEERING EXPERIMENT STATION Molecular and cellular imaging of bone biopsies using AI augmented deep UV Raman microscopy Active
2022 R21 CA21-003 LEE, HAKHO MASSACHUSETTS GENERAL HOSPITAL 3D Fourier Imaging System for High Throughput Analyses of Cancer Organoids Complete
2022 R21 RFA-CA-21-003 GIBBS, SUMMER LYNNE OREGON HEALTH & SCIENCE UNIVERSITY A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors Active
2022 R21 CA21-003 YAKOVLEV, VLADISLAV V TEXAS ENGINEERING EXPERIMENT STATION Molecular and cellular imaging of bone biopsies using AI augmented deep UV Raman microscopy Active
2022 R21 RFA-CA-21-003 NABA, ALEXANDRA UNIVERSITY OF ILLINOIS AT CHICAGO Enhanced mass-spectrometry-based approaches for in-depth profiling of the cancer extracellular matrix Active
2022 R21 CA21-003 KNOWLES, DAVID ARTHUR NEW YORK GENOME CENTER A CRISPR/Cas13 approach for identifying individual transcript isoform function in cancer Active
2022 R21 RFA-CA-21-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Molecular Sub-typing Breast Cancer Patients using a Liquid Biopsy Active
2022 R21 CA21-003 BELCHER, ANGELA M MASSACHUSETTS INSTITUTE OF TECHNOLOGY A cell-cycle induced genetic recorder for simultaneous recovery of cell divisions and lineage Complete
2022 R33 CA21-004 CHIU, BRIAN C-H UNIVERSITY OF CHICAGO A highly sensitive linear amplification based DNA methylation profiling technique for clinical cancer research Active
2022 R33 RFA-CA-21-004 LANDAU, DAN WEILL MEDICAL COLL OF CORNELL UNIV Expanding the GoT toolkit to link single-cell clonal genotypes with protein, transcriptomic, epigenomic and spatial phenotypes Active
2022 R21 CA21-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Molecular Sub-typing Breast Cancer Patients using a Liquid Biopsy Active
2022 R33 CA21-004 DRAKE, RICHARD R MEDICAL UNIVERSITY OF SOUTH CAROLINA Targeted Isolation and Identification of Sialylated Glycoproteins in Cancer Tissues, Cells and Biofluids Complete
2023 R61 RFA-CA-22-001 YAN, HAO ARIZONA STATE UNIVERSITY-TEMPE CAMPUS High-throughput, purification-free, and ultrasensitive transmembrane nanosensor arrays for digital counting of microRNA biomarkers of intact exosomes Active
2023 R61 RFA-CA-22-001 GAO, XIAOJING J STANFORD UNIVERSITY Program the Immune System against RAS-driven Cancer Active
2023 R33 RFA-CA-22-002 WEISSLEDER MD PHD, RALPH MASSACHUSETTS GENERAL HOSPITAL Bioorthogonal probe development for highly parallel in vivo imaging Active
2023 R61 RFA-CA-22-001 LUKER, GARY D UNIVERSITY OF MICHIGAN AT ANN ARBOR Integrated Imaging Tools for Intercellular Chemokine Signalling Active
2023 R33 RFA-CA-22-002 CUNNINGHAM, BRIAN T UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN Rapid, simple, and ultrasensitive quantitation of KRAS ctDNA at the point of care using CRISPR/Cas amplification and digital resolution biosensor microscopy Active
2023 R33 RFA-CA-22-002 VAN GALEN, PETER BRIGHAM AND WOMEN'S HOSPITAL Clonal analysis of cancer by mitochondrial DNA barcoding Active
2023 R61 RFA-CA-22-001 BRAVO CORDERO, JOSE JAVIER ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Intersectional genetics-based biosensors for dormant cancer cells Active
2023 R61 RFA-CA-22-001 SHAH, NEEL H COLUMBIA UNIV NEW YORK MORNINGSIDE A Generalizable Photo-Crosslinking Strategy to Identify Tyrosine Phosphatase Substrates Active
2023 R33 RFA-CA-22-002 JI, HANLEE P STANFORD UNIVERSITY Single cell modeling of cancer mutations Active
2023 R33 RFA-CA-22-002 ISSADORE, DAVID AARON UNIVERSITY OF PENNSYLVANIA Combining Machine Learning and Nanofluidic Technology for The Multiplexed Diagnosis of Pancreatic Adenocarcinoma Active
2023 R33 RFA-CA-22-004 BRUDNO, YEVGENY NORTH CAROLINA STATE UNIVERSITY RALEIGH MASTER Scaffolds for Rapid, Single-Step Manufacture and Prototyping of CAR-T cells Active
2023 R33 RFA-CA-22-002 MEYER, KATHRYN D DUKE UNIVERSITY A High-Throughput Screening Platform to Discover RNA Methylation Inhibitors Active
2023 R61 RFA-CA-22-001 DHAKAL, SOMA VIRGINIA COMMONWEALTH UNIVERSITY Single-Molecule High-Confidence Detection of miRNA Cancer Biomarkers Active
2023 R33 RFA-CA-22-004 LEVENSON, RICHARD M UNIVERSITY OF CALIFORNIA AT DAVIS CoreView and FIBI for rapid-onsite evaluation and molecular profiling of core-needle breast biopsies. Active
2023 R33 RFA-CA-22-002 KLEIN, ALLON MOSHE HARVARD MEDICAL SCHOOL Micro-capsules for versatile multiplexed cytometry Active

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