
Grants Awarded
Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.
New awards will be posted as they are issued.
Year![]() |
Award Type | Project # | RFA # | PI/Project Leader | Institution | Title | Status |
---|---|---|---|---|---|---|---|
2022 | R33 | CA269094 | CA21-004 | MOELLERING, RAYMOND E | UNIVERSITY OF CHICAGO | Single-Cell Protein Activity Profiling in Breast Cancer Cells and Tissues | Active |
2022 | R21 | CA272326 | CA21-003 | KELLY, RYAN T | BRIGHAM YOUNG UNIVERSITY | In-depth and label-free proteome profiling of hundreds of single cells per day | Active |
2022 | R33 | CA267221 | CA21-004 | NORMAN, THOMAS MAXWELL | SLOAN-KETTERING INST CAN RESEARCH | Systematic characterization of cancer variants using single-cell functional genomics | Active |
2022 | R21 | CA261775 | CA21-003 | LIN, QIAO | COLUMBIA UNIV NEW YORK MORNINGSIDE | A Practical Approach to Tumor-Specific Aptamers for B-Cell Hematologic Malignancies | Active |
2022 | R21 | CA261643 | CA21-005 | TANG, SINDY KAM-YAN | STANFORD UNIVERSITY | A micro-dissection platform for generating uniform-sized patient-derived tumor organoids (PDOs) for personalized cancer therapy | Active |
2022 | R21 | CA267222 | CA21-003 | LEE, HAKHO | MASSACHUSETTS GENERAL HOSPITAL | 3D Fourier Imaging System for High Throughput Analyses of Cancer Organoids | Complete |
2022 | R21 | CA269099 | CA21-003 | YAKOVLEV, VLADISLAV V | TEXAS ENGINEERING EXPERIMENT STATION | Molecular and cellular imaging of bone biopsies using AI augmented deep UV Raman microscopy | Active |
2022 | R21 | CA272345 | CA21-003 | KNOWLES, DAVID ARTHUR | NEW YORK GENOME CENTER | A CRISPR/Cas13 approach for identifying individual transcript isoform function in cancer | Active |
2022 | R21 | CA257980 | CA21-003 | BELCHER, ANGELA M | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | A cell-cycle induced genetic recorder for simultaneous recovery of cell divisions and lineage | Complete |
2022 | R33 | CA269100 | CA21-004 | CHIU, BRIAN C-H | UNIVERSITY OF CHICAGO | A highly sensitive linear amplification based DNA methylation profiling technique for clinical cancer research | Active |
2022 | R21 | CA272351 | CA21-003 | SOPER, STEVEN ALLAN | UNIVERSITY OF KANSAS LAWRENCE | Molecular Sub-typing Breast Cancer Patients using a Liquid Biopsy | Active |
2022 | R33 | CA267226 | CA21-004 | DRAKE, RICHARD R | MEDICAL UNIVERSITY OF SOUTH CAROLINA | Targeted Isolation and Identification of Sialylated Glycoproteins in Cancer Tissues, Cells and Biofluids | Complete |
2022 | R21 | CA269103 | CA21-003 | BLAINEY, PAUL CLARK | BROAD INSTITUTE, INC. | Stitch-seq for genome-wide pooled genomic screening with RNA-seq readout | Active |
2022 | R33 | CA272357 | CA21-004 | PAN, TAO | UNIVERSITY OF CHICAGO | Transfer RNA sequencing and application to cancer research and clinics | Active |
2022 | R21 | CA267260 | CA21-003 | ARMITAGE, BRUCE A | CARNEGIE-MELLON UNIVERSITY | Fluorescent gammaPNA Miniprobes for Imaging Telomeric RNA | Complete |
2022 | R21 | CA272014 | CA21-003 | SALIPANTE, STEPHEN J | UNIVERSITY OF WASHINGTON | Efficient, cost-effective, and ultrasensitive sequencing of somatic mutations | Active |
2022 | R33 | CA267258 | CA21-004 | LEE, ABRAHAM P | UNIVERSITY OF CALIFORNIA-IRVINE | Microfluidic Precision Engineered Artificial Antigen Presenting Cells for Cancer Immunotherapy | Active |
2022 | R21 | CA257816 | CA21-003 | COUNTER, CHRISTOPHER M | DUKE UNIVERSITY | Adapting K-MDS to detect KRAS-mutant ctDNA | Active |
2022 | R21 | CA272014 | CA21-003 | NABA, ALEXANDRA | UNIVERSITY OF ILLINOIS AT CHICAGO | Enhanced mass-spectrometry-based approaches for in-depth profiling of the cancer extracellular matrix | Active |
2022 | R21 | CA267012 | CA21-003 | SNYDER, JOSHUA CLAIR | DUKE UNIVERSITY | Mouse Paint: A massively combinatorial approach for illuminating tumor heterogeneity in True Color | Active |
2022 | R33 | CA261696 | CA21-004 | MERAJVER, SOFIA DIANA | UNIVERSITY OF MICHIGAN AT ANN ARBOR | Advanced development and validation of an in vitro platform to phenotype brain metastatic tumor cells using artificial intelligence | Active |
2022 | R21 | CA267245 | CA21-005 | SHIBATA, DARRYL K | UNIVERSITY OF SOUTHERN CALIFORNIA | Photolithographic Tumor DNA Isolation | Active |
2022 | R21 | CA257942 | CA21-003 | GIBBS, SUMMER LYNNE | OREGON HEALTH & SCIENCE UNIVERSITY | A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors | Active |
2022 | R33 | CA269015 | CA21-004 | ADEY, ANDREW | OREGON HEALTH & SCIENCE UNIVERSITY | Accessible high-throughput single-cell genome sequencing | Active |
2022 | R33 | CA267219 | CA21-004 | LANDAU, DAN | WEILL MEDICAL COLL OF CORNELL UNIV | Expanding the GoT toolkit to link single-cell clonal genotypes with protein, transcriptomic, epigenomic and spatial phenotypes | Active |
2022 | R21 | CA250999 | CA21-005 | BORGES, CHAD R | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS | Aliquot-level visual indicators of biospecimen exposure to thawed conditions | Complete |
2022 | R33 | CA258012 | CA21-004 | KARGINOV, ANDREI V | UNIVERSITY OF ILLINOIS AT CHICAGO | Optogenetic Control of Tumor Initiation and Tumor Progression in vivo | Active |
2022 | R33 | CA272321 | CA21-004 | WANG, TZA-HUEI JEFF | JOHNS HOPKINS UNIVERSITY | A low-cost, multiplexed digital high resolution melt platform for DNA methylation-based detection and identification of cancers in liquid biopsies | Active |
2022 | R21 | CA257864 | CA21-003 | BOYLE, ALAN P | UNIVERSITY OF MICHIGAN AT ANN ARBOR | High-throughput inverted reporter assay for characterization of silencers and enhancer blockers | Complete |
2022 | R21 | CA269091 | CA21-005 | BORGES, CHAD R | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS | Plate reader assays to forensically assess exposure of plasma and serum to thawed conditions | Active |
2022 | R33 | CA259451 | CA21-004 | NAEGLE, KRISTEN M | UNIVERSITY OF VIRGINIA | A synthetic toolkit for the recombinant production of tyrosine phosphorylated proteins and peptides | Active |
2022 | R21 | CA258008 | CA21-003 | SCARCELLI, GIULIANO | UNIV OF MARYLAND, COLLEGE PARK | Stimulated Brillouin Flow Cytometry for biomechanical assessment of metastatic potential | Complete |
2021 | R33 | CA257878 | RFA-CA-20-018 | HANSEN, ANDERS SEJR | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | Super-resolution microscopy for dynamic analysis of focal enhancer amplifications in cancer | Active |
2021 | R33 | CA261726 | CA20-018 | CHENG, JI-XIN | BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) | Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy | Complete |
2021 | R21 | CA251015 | RFA-CA-20-017 | STILL, AMANDA NICOLE HAYMOND | GEORGE MASON UNIVERSITY | New Hybrid Molecular Modalities Comprised of DNA-Origami and Interfering Peptides as Inhibitors of Protein-Protein Interactions | Active |
2021 | R33 | CA258016 | RFA-CA-20-018 | LIU, XUEFENG | OHIO STATE UNIVERSITY | Validating Urine Derived Cancer Cells (UDCC) -- Non-Invasive and Living Liquid Biopsies -- in Bladder Cancer Clinics | Active |
2021 | R21 | CA236686 | CA20-017 | FARIS, GREGORY W | NUMENTUS TECHNOLOGIES INC. | Decoding Individual Exosomes in Cancer | Complete |
2021 | R21 | CA255894 | RFA-CA-20-017 | XIAO, HAN | RICE UNIVERSITY | Development of Bone-Targeting Antibodies for Ewing Sarcoma Using Genetic Code Expansion | Active |
2021 | R44 | CA261523 | PAR-18-303 | HUNG, PAUL JU-SUNG | COMBINATI, INC. | Digital Melt Curve Analysis Platform for Longitudinal Cancer Patient Monitoring | Active |
2021 | R21 | CA255979 | CA20-017 | DIDENKO, VLADIMIR V | BAYLOR COLLEGE OF MEDICINE | In situ assay imaging nuclear RNA exosome activity for cancer studies | Complete |
2021 | R21 | CA256081 | RFA-CA-20-017 | SWAGER, TIMOTHY M | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | Innovative Droplet Lenses for NextGen Light Sensors of Biomarkers of Inflammation | Active |
2021 | R21 | CA251043 | CA20-017 | HOSHIKA, SHUICHI | FOUNDATION FOR APPLIED MOLECULAR EVOLUTN | High Quality Proteins with Multiple Post Translational Modifications | Complete |
2021 | R21 | CA261737 | CA20-017 | HAINER, SARAH JANE | UNIVERSITY OF PITTSBURGH AT PITTSBURGH | Using nanobodies to increase the sensitivity and resolution of chromatin profiling through uliCUT&RUN | Complete |
2021 | R21 | CA256082 | RFA-CA-20-017 | BAR-PELED, LIRON | MASSACHUSETTS GENERAL HOSPITAL | Chemical Proteomic Identification of Druggable Oncogenic Transcription Factors | Active |
2021 | R21 | CA256084 | CA20-017 | DI CARLO, DINO | UNIVERSITY OF CALIFORNIA LOS ANGELES | Lab on a particle technology for functional screening of therapeutic cells | Complete |
2021 | R21 | CA256128 | CA20-017 | DEININGER, MICHAEL W | VERSITI WISCONSIN, INC. | A Bioluminescent Assay for Direct Measurement of Sirtuin Activity in Cancer Cells | Complete |
2021 | R21 | CA258019 | RFA-CA-20-017 | CHEN, KAI | UNIVERSITY OF SOUTHERN CALIFORNIA | Novel Bisphosphonate PET Probes for Myeloma Bone Disease | Active |
2021 | R21 | CA258013 | CA20-019 | NAUTIYAL, SHIVANI | PRIME GENOMICS, INC. | Device for Preservation of Cell Free RNA in Saliva | Complete |
2021 | R21 | CA251027 | CA20-017 | SCHULMAN, REBECCA | JOHNS HOPKINS UNIVERSITY | Secretion responsive Hydrogels for Identification of Functional single T cells (SHIFT) | Complete |
2021 | R33 | CA247700 | RFA-CA-20-018 | JI, HANLEE P | STANFORD UNIVERSITY | Multimodal iterative sequencing of cancer genomes and single tumor cells | Active |