Grants Awarded
Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.
New awards will be posted as they are issued.
Year | Award Type | Project # | RFA # | PI/Project Leader | Institution | Title | Status |
---|---|---|---|---|---|---|---|
2019 | R21 | CA240580 | RFA-CA-18-002 | MONTAGNA, CRISTINA | ALBERT EINSTEIN COLLEGE OF MEDICINE | Development of a high-resolution mapping platform for HPV DNA integration in premalignant lesions | Complete |
2019 | R33 | CA235597 | RFA-CA-18-003 | SOPER, STEVEN ALLAN | UNIVERSITY OF KANSAS LAWRENCE | Increased Sensitivity of Minimal Residual Disease Monitoring using Peripheral Blood in Pediatric Patients with Acute Lymphoblastic Leukemia | Complete |
2019 | R21 | CA240219 | RFA-CA-18-004 | ANDRES-MARTIN, LAURA | NEW YORK STEM CELL FOUNDATION | Establishing efficient technologies for ovarian cancer organoid derivation from fresh tumor resections | Complete |
2019 | R33 | CA240201 | RFA-CA-18-003 | VAN DAM, ROBERT MICHAEL | UNIVERSITY OF CALIFORNIA LOS ANGELES | Optimization and validation of integrated microscale technologies for low-cost; automated production of PET molecular imaging tracers for cancer research | Complete |
2019 | R21 | CA240199 | RFA-CA-18-002 | O'NEILL, RACHEL | UNIVERSITY OF CONNECTICUT STORRS | Development and Utilization of Splice-specific Antibodies | Complete |
2019 | R33 | CA235302 | RFA-CA-18-003 | DE VLAMINCK, IWIJN | CORNELL UNIVERSITY | Spatially Resolved Metagenomics to Explore Tumor-Microbiome Interactions in Human Colorectal Cancer | Complete |
2019 | R21 | CA217662 | RFA-CA-18-002 | IM, HYUNGSOON | MASSACHUSETTS GENERAL HOSPITAL | Nano-plasmonic technology for high-throughput single exosome analyses | Complete |
2019 | R21 | CA240162 | RFA-CA-18-002 | KEUNG, ALBERT | NORTH CAROLINA STATE UNIVERSITY RALEIGH | Intracellular CRISPR gRNA assembly for massively multiplexed; one pot; (epi)genetic screening | Complete |
2019 | R21 | CA240148 | RFA-CA-18-002 | ANGEL, PEGGY M | MEDICAL UNIVERSITY OF SOUTH CAROLINA | Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins | Complete |
2019 | R43 | CA239967 | PAR-18-303 | BROWN, MARK T | CLAREMONT BIOSOLUTIONS, LLC | Rapid sample preparation method for high molecular weight DNA from tumor tissues suitable for structural variant analysis | Complete |
2019 | R43 | CA236167 | PAR-18-303 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | Development of the High Throughput APT-SNAP Platform for Rapid Identification ofNuclease-Resistant RNA Aptamers against p53 Missense Mutations | Complete |
2019 | R21 | CA236690 | RFA-CA-18-002 | KIM, HYUN JUNG | UNIVERSITY OF TEXAS, AUSTIN | A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk | Complete |
2019 | R33 | CA236687 | RFA-CA-18-003 | BREUNIG, JOSHUA JOHN | CEDARS-SINAI MEDICAL CENTER | GESTALT Barcoding and Single-cell Transcriptomics of Tumor Cell Evolution in Personalized Tumor Models | Complete |
2019 | R21 | CA236685 | RFA-CA-18-002 | MANALIS, SCOTT R | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | Building microenvironment-containing organoids from patient samples with single-cell precision | Complete |
2019 | R21 | CA229069 | RFA-CA-18-002 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants | Complete |
2019 | R21 | CA236652 | RFA-CA-18-004 | SINGAMANENI, SRIKANTH | WASHINGTON UNIVERSITY | METAL-ORGANIC FRAMEWORK AS PROTECTIVE COATING FOR CANCER BIOSPECIMEN PRESERVATION | Complete |
2019 | R33 | CA225498 | RFA-CA-18-003 | CHEN, SIDI | YALE UNIVERSITY | Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers | Complete |
2019 | R21 | CA236640 | RFA-CA-18-002 | BHATNAGAR, PARIJAT | SRI INTERNATIONAL | T-cell Biofactories for targeting interstitial fluid pressure | Complete |
2019 | R33 | CA225458 | RFA-CA-18-003 | KETTENBACH, ARMINJA NADINE | DARTMOUTH COLLEGE | Activity based profiling of Phosphoprotein phosphatases in cancer using mass spectrometry-based proteomics | Complete |
2019 | R33 | CA229042 | RFA-CA-18-003 | SCHNECK, JONATHAN P | JOHNS HOPKINS UNIVERSITY | A high-throughput nanoparticle assay to characterize cancer neoepitope-specific T cells | Complete |
2019 | R21 | CA236594 | RFA-CA-18-002 | GARBER, MANUEL | UNIV OF MASSACHUSETTS MED SCH WORCESTER | A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells | Complete |
2019 | R21 | CA236561 | RFA-CA-18-002 | WEISSLEDER, RALPH | MASSACHUSETTS GENERAL HOSPITAL | Single Circulating Vesicle Analysis for Early Cancer Detection | Complete |
2018 | R43 | CA236142 | PAR-18-303 | SCHOETTLE, LOUIS | GEMNEO BIOSCIENCE, INC. | Origami Nanoprobes for Large-Scale Single-Cell Analysis of Lymphocytes | Complete |
2018 | R43 | CA236097 | PAR-18-303 | LIM, MARK | AMBERGEN, INC | Highly Multiplexed Nanoscale Mass Spectrometric Imaging of Cancer Tissues | Active |
2019 | R43 | CA236177 | PAR-18-303 | KASOJI, SANDEEP | TRIANGLE BIOTECHNOLOGY, INC. | SBIR: Technology for Overcoming Bottlenecks in Chromatin Extraction from Challenging Biological Samples | Complete |
2018 | R43 | CA236101 | PAR-18-303 | LEE, LY JAMES | NANOMATERIAL INNOVATION, LTD | Molecular Beacons in Lipoplex Nanoparticles for Extracellular Vesicles Based Cancer Diagnosis | Complete |
2019 | R43 | CA236103 | PAR-18-303 | KHODAVERDIAN, VARANDT Y. | NUPROBE USA, INC. | Allele selective enrichment for targeted profiling of rare cancer mutations via low-depth sequencing | Complete |
2019 | R21 | CA235340 | RFA-CA-18-002 | ZHU, YAZHEN | UNIVERSITY OF CALIFORNIA LOS ANGELES | Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs | Complete |
2019 | R33 | CA235326 | RFA-CA-18-005 | LEI, YUGUO | UNIVERSITY OF NEBRASKA LINCOLN | A Single Conical Tube Device for Precision CAR-T Cells Manufacturing | Complete |
2019 | R21 | CA235305 | RFA-CA-18-002 | WU, YUN | STATE UNIVERSITY OF NEW YORK AT BUFFALO | Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection | Complete |
2019 | R21 | CA235303 | RFA-CA-18-002 | YAMAMOTO, KEITH ROBERT | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer | Complete |
2019 | R33 | CA225549 | RFA-CA-18-003 | TAVANA, HOSSEIN | UNIVERSITY OF AKRON | A High Throughput Human Tumor Modeling Technology for Cancer Drug Discovery | Complete |
2019 | R21 | CA235285 | RFA-CA-18-002 | KENTSIS, ALEX | SLOAN-KETTERING INST CAN RESEARCH | Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics | Complete |
2019 | R33 | CA235254 | RFA-CA-18-003 | FIOLKA, RETO PAUL | UT SOUTHWESTERN MEDICAL CENTER | Multiscale microscope for 3D cancer imaging in model organisms and organoids | Complete |
2019 | R21 | CA223727 | RFA-CA-18-002 | HUANG, XIAOHUA | UNIVERSITY OF CALIFORNIA, SAN DIEGO | Technology for measuring telomere length of individual chromosomes of single cancer cells | Complete |
2020 | R43 | CA243757 | PAR-18-303 | ERVIN, ERIC | ELECTRONIC BIOSCIENCES, INC. | N6-Methyl-2-O-Methyladenosine Sequencing | Complete |
2020 | R43 | CA250805 | PAR-18-303 | WANG, SHA | VIVID TECHNOLOGIES | New specific and rapid assay for in situ apoptosis labeling for cancer studies | Complete |
2020 | R33 | CA247739 | RFA-CA-19-020 | MATRIX BHATNAGAR, PARIJAT | SRI INTERNATIONAL | T-cell Biofactories For Targeting Extracellular Matrix | Active |
2020 | R21 | CA240220 | RFA-CA-19-019 | ALEXANDRAKIS, GEORGIOS | UNIVERSITY OF TEXAS ARLINGTON | Nanotechnology Enabled Selection Of MHC-peptide Ligands To Personalize Cancer Therapy | Active |
2020 | R21 | CA247638 | RFA-CA-19-019 | LIANG, FU-SEN | CASE WESTERN RESERVE UNIVERSITY | Spatiotemporal Epitranscriptome Editing Technology | Active |
2020 | R33 | CA236670 | RFA-CA-19-020 | HIGGINSON, DANIEL | SLOAN-KETTERING INST CAN RESEARCH | Comprehensive Breakpoint Analyses For Simultaneous Quantification Of All Dna Double Strand Break Repair Pathways | Complete |
2020 | R33 | CA236681 | RFA-CA-19-020 | WEI, CHIA-LIN | JACKSON LABORATORY | Advancing Ultra Long-read Sequencing And Chromatin Interaction Analyses For Chromosomal And Extrachromosomal Structural Variation Characterization In Cancer | Complete |
2020 | R43 | CA236167 | PAR-18-303 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | Development Of The High Throughput Apt-snap Platform For Rapid Identification Ofnuclease-resistant Rna Aptamers Against P53 Missense Mutations | Active |
2018 | R21 | CA214285 | RFA-CA-17-010 | MAILLOUX, ADAM WILLIAM | H. LEE MOFFITT CANCER CTR & RES INST | Autohistomagnetic Isolation of Tumor-reactive T-cells | Complete |
2018 | R21 | CA229057 | RFA-CA-17-010 | FU, XIAO-AN | UNIVERSITY OF LOUISVILLE | A microreactor chip platform for quantitative analysis of unsaturated aldehydes in exhaled breath | Complete |
2018 | R21 | CA229044 | RFA-CA-17-010 | ABBOTT, KAREN L | UNIV OF ARKANSAS FOR MED SCIS | Novel platform linking cancer-specific glycosylation with cell signaling outcomes | Complete |
2018 | R21 | CA229037 | RFA-CA-17-012 | GULLEY, MARGARET L | UNIV OF NORTH CAROLINA CHAPEL HILL | EndoGenus Toolkit: A Biometric Method for Absolute Quantification of Tumor Markers by Massive Parallel Sequencing | Complete |
2018 | R21 | CA229027 | RFA-CA-17-012 | SKARDAL, ALEKSANDER (contact); STROWD, ROY ERVIN | WAKE FOREST UNIVERSITY HEALTH SCIENCES | Predicting Tumor Heterogeneity Evolution After Therapy In Patient-Derived Ex Vivo Glioblastoma Organoids | Complete |
2018 | R33 | CA223947 | RFA-CA-17-011 | BROWN, BRIAN D | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI | Pro-Codes: A novel vector and cell barcoding technology | Complete |
2018 | R33 | CA229023 | RFA-CA-17-011 | TEWARI, MUNEESH (contact); WALTER, NILS G | UNIVERSITY OF MICHIGAN AT ANN ARBOR | Optimization and Validation of Single-Molecule Kinetic Fingerprinting Technology for Rapid, Ultra-Specific Detection of Cancer Mutations | Complete |