Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Year Award Type Project # RFA # PI/Project Leader Institution Title Statussort ascending
2021 R21 RFA-CA-20-017 WILSON, GERALD M UNIVERSITY OF MARYLAND BALTIMORE Suppressing oncogenic RNA regulons using engineered zinc finger ribonucleases Active
2022 R21 RFA-CA-21-003 NABA, ALEXANDRA UNIVERSITY OF ILLINOIS AT CHICAGO Enhanced mass-spectrometry-based approaches for in-depth profiling of the cancer extracellular matrix Active
2022 R33 CA21-004 NORMAN, THOMAS MAXWELL SLOAN-KETTERING INST CAN RESEARCH Systematic characterization of cancer variants using single-cell functional genomics Active
2021 R21 RFA-CA-20-017 ZHANG, FANGLIANG UNIVERSITY OF MIAMI SCHOOL OF MEDICINE Targeted degradation of proteins by affinity peptide conjugated ubiquitin (APCU) Active
2022 R33 RFA-CA-21-004 LANDAU, DAN WEILL MEDICAL COLL OF CORNELL UNIV Expanding the GoT toolkit to link single-cell clonal genotypes with protein, transcriptomic, epigenomic and spatial phenotypes Active
2022 R21 CA21-003 LEE, HAKHO MASSACHUSETTS GENERAL HOSPITAL 3D Fourier Imaging System for High Throughput Analyses of Cancer Organoids Active
2021 R21 RFA-CA-20-017 STILL, AMANDA NICOLE HAYMOND GEORGE MASON UNIVERSITY New Hybrid Molecular Modalities Comprised of DNA-Origami and Interfering Peptides as Inhibitors of Protein-Protein Interactions Active
2023 R61 RFA-CA-22-001 YAN, HAO ARIZONA STATE UNIVERSITY-TEMPE CAMPUS High-throughput, purification-free, and ultrasensitive transmembrane nanosensor arrays for digital counting of microRNA biomarkers of intact exosomes Active
2022 R21 CA21-003 BELCHER, ANGELA M MASSACHUSETTS INSTITUTE OF TECHNOLOGY A cell-cycle induced genetic recorder for simultaneous recovery of cell divisions and lineage Active
2021 R21 RFA-CA-20-017 XIAO, HAN RICE UNIVERSITY Development of Bone-Targeting Antibodies for Ewing Sarcoma Using Genetic Code Expansion Active
2020 R33 RFA-CA-19-020 RECHT, MICHAEL PALO ALTO RESEARCH CENTER High-Throughput Screening Platform for Cancer Drug Discovery Active
2022 R21 RFA-CA-21-003 KELLY, RYAN T BRIGHAM YOUNG UNIVERSITY In-depth and label-free proteome profiling of hundreds of single cells per day Active
2022 R33 CA21-004 DRAKE, RICHARD R MEDICAL UNIVERSITY OF SOUTH CAROLINA Targeted Isolation and Identification of Sialylated Glycoproteins in Cancer Tissues, Cells and Biofluids Active
2021 R21 RFA-CA-20-017 SWAGER, TIMOTHY M MASSACHUSETTS INSTITUTE OF TECHNOLOGY Innovative Droplet Lenses for NextGen Light Sensors of Biomarkers of Inflammation Active
2023 R61 RFA-CA-22-001 LUKER, GARY D UNIVERSITY OF MICHIGAN AT ANN ARBOR Integrated Imaging Tools for Intercellular Chemokine Signalling Active
2022 R21 CA21-003 ARMITAGE, BRUCE A CARNEGIE-MELLON UNIVERSITY Fluorescent gammaPNA Miniprobes for Imaging Telomeric RNA Active
2021 R21 RFA-CA-20-017 BAR-PELED, LIRON MASSACHUSETTS GENERAL HOSPITAL Chemical Proteomic Identification of Druggable Oncogenic Transcription Factors Active
2023 R61 RFA-CA-22-001 BRAVO CORDERO, JOSE JAVIER ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Intersectional genetics-based biosensors for dormant cancer cells Active
2022 R21 CA21-003 COUNTER, CHRISTOPHER M DUKE UNIVERSITY Adapting K-MDS to detect KRAS-mutant ctDNA Active
2021 R21 RFA-CA-20-017 CHEN, KAI UNIVERSITY OF SOUTHERN CALIFORNIA Novel Bisphosphonate PET Probes for Myeloma Bone Disease Active
2023 R33 RFA-CA-22-004 BRUDNO, YEVGENY NORTH CAROLINA STATE UNIVERSITY RALEIGH MASTER Scaffolds for Rapid, Single-Step Manufacture and Prototyping of CAR-T cells Active
2022 R33 CA21-004 MERAJVER, SOFIA DIANA UNIVERSITY OF MICHIGAN AT ANN ARBOR Advanced development and validation of an in vitro platform to phenotype brain metastatic tumor cells using artificial intelligence Active
2021 R33 RFA-CA-20-018 JI, HANLEE P STANFORD UNIVERSITY Multimodal iterative sequencing of cancer genomes and single tumor cells Active
2023 R33 RFA-CA-22-002 KLEIN, ALLON MOSHE HARVARD MEDICAL SCHOOL Micro-capsules for versatile multiplexed cytometry Active
2022 R33 CA21-004 ADEY, ANDREW OREGON HEALTH & SCIENCE UNIVERSITY Accessible high-throughput single-cell genome sequencing Active
2021 R33 RFA-CA-20-018 GARTNER, ZEV JORDAN UNIVERSITY OF CALIFORNIA, SAN FRANCISCO Universal Sample Multiplexing for Single Cell Analysis Active
2022 R33 RFA-CA-21-004 LEE, ABRAHAM P UNIVERSITY OF CALIFORNIA-IRVINE Microfluidic Precision Engineered Artificial Antigen Presenting Cells for Cancer Immunotherapy Active
2022 R33 CA21-004 KARGINOV, ANDREI V UNIVERSITY OF ILLINOIS AT CHICAGO Optogenetic Control of Tumor Initiation and Tumor Progression in vivo Active
2021 R33 RFA-CA-20-020 HAUN, JERED BRACKSTON UNIVERSITY OF CALIFORNIA-IRVINE Microfluidic tumor tissue processing platform for single cell diagnostics Active
2023 R61 RFA-CA-22-001 SHIRURE, VENKTESH UNIVERSITY OF CALIFORNIA AT DAVIS Microfluidic technology to isolate tumoricidal T-cells from peripheral blood Active
2022 R21 CA21-005 BORGES, CHAD R ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Plate reader assays to forensically assess exposure of plasma and serum to thawed conditions Active
2021 R33 RFA-CA-20-018 SEELIG, GEORG UNIVERSITY OF WASHINGTON Joint receptor and protein expression immunophenotyping through split-pool barcoding Active
2022 R21 RFA-CA-21-003 YAKOVLEV, VLADISLAV V TEXAS ENGINEERING EXPERIMENT STATION Molecular and cellular imaging of bone biopsies using AI augmented deep UV Raman microscopy Active
2022 R33 CA21-004 MOELLERING, RAYMOND E UNIVERSITY OF CHICAGO Single-Cell Protein Activity Profiling in Breast Cancer Cells and Tissues Active
2021 R33 RFA-CA-20-018 GREENBERG, JOEL DUKE UNIVERSITY Multimodality X-ray transmission and diffraction scanner for molecular analysis of cancer specimens Active
2022 R21 RFA-CA-21-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Molecular Sub-typing Breast Cancer Patients using a Liquid Biopsy Active
2022 R21 CA21-003 LIN, QIAO COLUMBIA UNIV NEW YORK MORNINGSIDE A Practical Approach to Tumor-Specific Aptamers for B-Cell Hematologic Malignancies Active
2021 R33 RFA-CA-20-018 HANSEN, ANDERS SEJR MASSACHUSETTS INSTITUTE OF TECHNOLOGY Super-resolution microscopy for dynamic analysis of focal enhancer amplifications in cancer Active
2020 R21 RFA-CA-19-019 ALEXANDRAKIS, GEORGIOS UNIVERSITY OF TEXAS ARLINGTON Nanotechnology Enabled Selection Of MHC-peptide Ligands To Personalize Cancer Therapy Active
2023 R33 RFA-CA-22-002 LABAER, JOSHUA ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Multiplex In-Solution Protein Array (MISPA) for high throughput, quantitative, early profiling of pathogen-induced head and neck Active
2022 R33 CA21-004 CHIU, BRIAN C-H UNIVERSITY OF CHICAGO A highly sensitive linear amplification based DNA methylation profiling technique for clinical cancer research Active
2021 R33 RFA-CA-20-018 LIU, XUEFENG OHIO STATE UNIVERSITY Validating Urine Derived Cancer Cells (UDCC) -- Non-Invasive and Living Liquid Biopsies -- in Bladder Cancer Clinics Active
2020 R33 RFA-CA-19-020 MATRIX BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories For Targeting Extracellular Matrix Active
2022 R21 RFA-CA-21-005 SHIBATA, DARRYL K UNIVERSITY OF SOUTHERN CALIFORNIA Photolithographic Tumor DNA Isolation Active
2022 R21 CA21-003 BLAINEY, PAUL CLARK BROAD INSTITUTE, INC. Stitch-seq for genome-wide pooled genomic screening with RNA-seq readout Active
2021 R21 CA20-017 HOSHIKA, SHUICHI FOUNDATION FOR APPLIED MOLECULAR EVOLUTN High Quality Proteins with Multiple Post Translational Modifications Active
2020 R21 RFA-CA-19-021 GUPTA, GAUTAM UNIVERSITY OF LOUISVILLE Bio Cargos: Capture And Release Gels For Optimized Storage Of Cancer Biospecimens Active
2023 R61 RFA-CA-22-001 GAO, XIAOJING J STANFORD UNIVERSITY Program the Immune System against RAS-driven Cancer Active
2022 R21 CA21-005 TANG, SINDY KAM-YAN STANFORD UNIVERSITY A micro-dissection platform for generating uniform-sized patient-derived tumor organoids (PDOs) for personalized cancer therapy Active
2023 R33 RFA-CA-22-002 CUNNINGHAM, BRIAN T UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN Rapid, simple, and ultrasensitive quantitation of KRAS ctDNA at the point of care using CRISPR/Cas amplification and digital resolution biosensor microscopy Active

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