
Grants Awarded
Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.
New awards will be posted as they are issued.
Year![]() |
Award Type | Project # | RFA # | PI/Project Leader | Institution | Title | Status |
---|---|---|---|---|---|---|---|
2019 | R21 | CA229069 | RFA-CA-18-002 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | SNAP-X: Development of a Mutagenesis Strategy and High Density Protein Array to Comprehensively Display Protein Variants | Active |
2019 | R21 | CA240162 | RFA-CA-18-002 | KEUNG, ALBERT | NORTH CAROLINA STATE UNIVERSITY RALEIGH | Intracellular CRISPR gRNA assembly for massively multiplexed; one pot; (epi)genetic screening | Active |
2019 | R33 | CA235597 | RFA-CA-18-003 | SOPER, STEVEN ALLAN | UNIVERSITY OF KANSAS LAWRENCE | Increased Sensitivity of Minimal Residual Disease Monitoring using Peripheral Blood in Pediatric Patients with Acute Lymphoblastic Leukemia | Active |
2019 | R21 | CA235285 | RFA-CA-18-002 | KENTSIS, ALEX | SLOAN-KETTERING INST CAN RESEARCH | Multi-dimensional targeted mass spectrometry technology for pathway-scale functional proteomics | Active |
2019 | R21 | CA240199 | RFA-CA-18-002 | O'NEILL, RACHEL | UNIVERSITY OF CONNECTICUT STORRS | Development and Utilization of Splice-specific Antibodies | Active |
2019 | R33 | CA236687 | RFA-CA-18-003 | BREUNIG, JOSHUA JOHN | CEDARS-SINAI MEDICAL CENTER | GESTALT Barcoding and Single-cell Transcriptomics of Tumor Cell Evolution in Personalized Tumor Models | Active |
2019 | R21 | CA235303 | RFA-CA-18-002 | YAMAMOTO, KEITH ROBERT | UNIVERSITY OF CALIFORNIA, SAN FRANCISCO | CasCUT&RUN: An in vivo method to analyze locus-specific protein complexes driving transcription of target genes in cancer | Active |
2019 | R21 | CA240580 | RFA-CA-18-002 | MONTAGNA, CRISTINA | ALBERT EINSTEIN COLLEGE OF MEDICINE | Development of a high-resolution mapping platform for HPV DNA integration in premalignant lesions | Active |
2019 | R33 | CA240201 | RFA-CA-18-003 | VAN DAM, ROBERT MICHAEL | UNIVERSITY OF CALIFORNIA LOS ANGELES | Optimization and validation of integrated microscale technologies for low-cost; automated production of PET molecular imaging tracers for cancer research | Active |
2019 | R21 | CA235305 | RFA-CA-18-002 | WU, YUN | STATE UNIVERSITY OF NEW YORK AT BUFFALO | Exosome-Protein-microRNA-OneStop (Exo-PROS) biosensor: a new liquid biopsy for cancer screening and early detection | Active |
2019 | R33 | CA225458 | RFA-CA-18-003 | KETTENBACH, ARMINJA NADINE | DARTMOUTH COLLEGE | Activity based profiling of Phosphoprotein phosphatases in cancer using mass spectrometry-based proteomics | Active |
2019 | R21 | CA236652 | RFA-CA-18-004 | SINGAMANENI, SRIKANTH | WASHINGTON UNIVERSITY | METAL-ORGANIC FRAMEWORK AS PROTECTIVE COATING FOR CANCER BIOSPECIMEN PRESERVATION | Active |
2019 | R21 | CA235340 | RFA-CA-18-002 | ZHU, YAZHEN | UNIVERSITY OF CALIFORNIA LOS ANGELES | Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs | Active |
2019 | R33 | CA225498 | RFA-CA-18-003 | CHEN, SIDI | YALE UNIVERSITY | Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers | Active |
2019 | R21 | CA240219 | RFA-CA-18-004 | ANDRES-MARTIN, LAURA | NEW YORK STEM CELL FOUNDATION | Establishing efficient technologies for ovarian cancer organoid derivation from fresh tumor resections | Active |
2019 | R43 | CA236103 | PAR-18-303 | KHODAVERDIAN, VARANDT Y. | NUPROBE USA, INC. | Allele selective enrichment for targeted profiling of rare cancer mutations via low-depth sequencing | Complete |
2019 | R21 | CA236561 | RFA-CA-18-002 | WEISSLEDER, RALPH | MASSACHUSETTS GENERAL HOSPITAL | Single Circulating Vesicle Analysis for Early Cancer Detection | Active |
2019 | R33 | CA225549 | RFA-CA-18-003 | TAVANA, HOSSEIN | UNIVERSITY OF AKRON | A High Throughput Human Tumor Modeling Technology for Cancer Drug Discovery | Active |
2019 | R33 | CA235326 | RFA-CA-18-005 | LEI, YUGUO | UNIVERSITY OF NEBRASKA LINCOLN | A Single Conical Tube Device for Precision CAR-T Cells Manufacturing | Active |
2019 | R43 | CA236167 | PAR-18-303 | WARREN, CHRISTOPHER L | PROTEOVISTA, LLC | Development of the High Throughput APT-SNAP Platform for Rapid Identification ofNuclease-Resistant RNA Aptamers against p53 Missense Mutations | NCE |
2019 | R21 | CA236594 | RFA-CA-18-002 | GARBER, MANUEL | UNIV OF MASSACHUSETTS MED SCH WORCESTER | A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells | Active |
2019 | R33 | CA229042 | RFA-CA-18-003 | SCHNECK, JONATHAN P | JOHNS HOPKINS UNIVERSITY | A high-throughput nanoparticle assay to characterize cancer neoepitope-specific T cells | Active |
2019 | R43 | CA236177 | PAR-18-303 | KASOJI, SANDEEP | TRIANGLE BIOTECHNOLOGY, INC. | SBIR: Technology for Overcoming Bottlenecks in Chromatin Extraction from Challenging Biological Samples | Complete |
2019 | R21 | CA236640 | RFA-CA-18-002 | BHATNAGAR, PARIJAT | SRI INTERNATIONAL | T-cell Biofactories for targeting interstitial fluid pressure | Active |
2020 | R33 | CA236670 | RFA-CA-19-020 | HIGGINSON, DANIEL | SLOAN-KETTERING INST CAN RESEARCH | Comprehensive Breakpoint Analyses For Simultaneous Quantification Of All Dna Double Strand Break Repair Pathways | Active |
2020 | R21 | CA236612 | RFA-CA-19-019 | REVZIN, ALEXANDER | MAYO CLINIC ROCHESTER | A microfluidic cell culture platform for personalizing pancreatic cancer therapies | Active |
2020 | R33 | CA246448 | RFA-CA-19-020 | HALL, ADAM ROGER | WAKE FOREST UNIVERSITY HEALTH SCIENCES | Detecting diverse nucleic acid biomarkers of cancer with solid-state nanopores | Active |
2020 | R33 | CA247669 | RFA-CA-19-022 | HASHAM, MUNEER GULAMHUSEIN | JACKSON LABORATORY | Impact of Genetic Diversity on Human Xenograft Tumor Growth | Active |
2020 | R21 | CA240185 | RFA-CA-19-019 | LI, WEI | TEXAS TECH UNIVERSITY | Fractionation And Profiling Of Heterogeneous Circulating Tumor Cells Using A Hyperuniform- Structured Microchip | Active |
2020 | R21 | CA236653 | RFA-CA-19-019 | ISSADORE, DAVID AARON | UNIVERSITY OF PENNSYLVANIA | High Throughput Digital Droplet ELISA for Ultrasensitive Multiplexed Diagnostics | Active |
2020 | R33 | CA235294 | RFA-CA-19-020 | WANG, SHAOPENG | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS | A Virion-Display Oscillator Array and Detection Platform for Quantification of Transmembrane Protein Binding Kinetics | Active |
2020 | R43 | CA243757 | PAR-18-303 | ERVIN, ERIC | ELECTRONIC BIOSCIENCES, INC. | N6-Methyl-2-O-Methyladenosine Sequencing | Active |
2020 | R21 | CA247638 | RFA-CA-19-019 | LIANG, FU-SEN | CASE WESTERN RESERVE UNIVERSITY | Spatiotemporal Epitranscriptome Editing Technology | Active |
2020 | R21 | CA240214 | RFA-CA-19-019 | CICERONE, MARCUS T | GEORGIA INSTITUTE OF TECHNOLOGY | Label-Free Cell-Resolved Metabolomics for Tumor Microscopy | Active |
2020 | R44 | CA247353 | PAR-18-303 | FRIEDA, KIRSTEN | SPATIAL GENOMICS, INC. | Spatial and single cell analysis of tumor microenvironment by seqFISH+ | Active |
2020 | R44 | CA236097 | PAR-18-303 | LIM, MARK | AMBERGEN, INC | Highly Multiplexed Nanoscale Mass Spectrometric Imaging Of Cancer Tissues | Active |
2020 | R21 | CA246358 | RFA-CA-19-019 | SEELIG, GEORG | UNIVERSITY OF WASHINGTON | High-resolution spatial transcriptomics through light patterning | Active |
2020 | R43 | CA250805 | PAR-18-303 | WANG, SHA | VIVID TECHNOLOGIES | New specific and rapid assay for in situ apoptosis labeling for cancer studies | Active |
2020 | R43 | CA250885 | PAR-18-303 | REDER, NICHOLAS | LIGHTSPEED MICROSCOPY, INC. | Open-top Light-sheet Microscopy For Non-destructive 3d Pathology Of Prostate Biopsies | Active |
2020 | R21 | CA247671 | RFA-CA-19-019 | MARTO, JARROD A | DANA-FARBER CANCER INST | Tools for DUB Drug Discovery | Active |
2020 | R21 | CA240220 | RFA-CA-19-019 | ALEXANDRAKIS, GEORGIOS | UNIVERSITY OF TEXAS ARLINGTON | Nanotechnology Enabled Selection Of MHC-peptide Ligands To Personalize Cancer Therapy | Active |
2020 | R21 | CA251052 | RFA-CA-19-019 | SHVETS, GENNADY | CORNELL UNIVERSITY | Phenotypic Assay For Drug Discovery And Personalized Medicine Based On Real-time Vibrational Spectroscopy Enhanced By Plasmonic Metasurfaces | Active |
2020 | R33 | CA240181 | RFA-CA-19-020 | COOKS, ROBERT GRAHAM | PURDUE UNIVERSITY | Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer using Pathology Biopsies | Active |
2020 | R33 | CA247739 | RFA-CA-19-020 | MATRIX BHATNAGAR, PARIJAT | SRI INTERNATIONAL | T-cell Biofactories For Targeting Extracellular Matrix | Active |
2020 | R21 | CA225493 | RFA-CA-19-019 | TEWARI, MUNEESH | UNIVERSITY OF MICHIGAN AT ANN ARBOR | Highly Specific, Amplification-free, Single-molecule Counting Of Rare Methylated Dna Cancer Biomarkers | Active |
2020 | R33 | CA240191 | RFA-CA-19-020 | RECHT, MICHAEL | PALO ALTO RESEARCH CENTER | High-Throughput Screening Platform for Cancer Drug Discovery | Active |
2020 | R33 | CA240181 | RFA-CA-19-020 | COOKS, ROBERT GRAHAM | PURDUE UNIVERSITY | Advanced Development Of Desorption Electrospray Ionization Mass Spectrometry For Intraoperative Molecular Diagnosis Of Brain Cancer Using Pathology Biopsies | Active |
2020 | R33 | CA251037 | RFA-CA-19-020 | WANG, SIYUAN | YALE UNIVERSITY | Multiplexed Imaging Of Chromatin Folding And Rna Profiles In Cancer | Active |
2020 | R33 | CA246363 | RFA-CA-19-020 | LEVINSON, NICHOLAS MARK | UNIVERSITY OF MINNESOTA | Time-resolved FRET-based allostery sensors for any protein kinase drug target | Active |
2020 | R21 | CA251042 | RFA-CA-19-021 | GUPTA, GAUTAM | UNIVERSITY OF LOUISVILLE | Bio Cargos: Capture And Release Gels For Optimized Storage Of Cancer Biospecimens | Active |