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Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Year Award Type Project # RFA # PI/Project Leader Institution Title Statussort descending
2018 R21 CA228948 RFA-CA-17-010 SCHIBEL, ANNA ELECTRONIC BIOSCIENCES, INC. Microsatellite Sequencing to Enable Cancer Genotyping Active
2020 R33 CA240191 RFA-CA-19-020 RECHT, MICHAEL PALO ALTO RESEARCH CENTER High-Throughput Screening Platform for Cancer Drug Discovery Active
2019 R21 CA235340 RFA-CA-18-002 ZHU, YAZHEN UNIVERSITY OF CALIFORNIA LOS ANGELES Click Chemistry-Mediated Microfluidic Sorting for HCC CTCs Active
2018 R21 CA223715 RFA-CA-17-010 SHI, TUJIN BATTELLE PACIFIC NORTHWEST LABORATORIES An ultrasensitive targeted mass spectrometry system for proteomics analysis of single cells Active
2020 R33 CA246363 RFA-CA-19-020 LEVINSON, NICHOLAS MARK UNIVERSITY OF MINNESOTA Time-resolved FRET-based allostery sensors for any protein kinase drug target Active
2019 R21 CA236561 RFA-CA-18-002 WEISSLEDER, RALPH MASSACHUSETTS GENERAL HOSPITAL Single Circulating Vesicle Analysis for Early Cancer Detection Active
2018 R21 CA223887 RFA-CA-17-010 SMITH, LLOYD M UNIVERSITY OF WISCONSIN-MADISON Novel NeuCode Tagging Reagents for Identification and Quantification of Intact Proteoforms in Cancer Tissues Active
2017 R21 CA217695 RFA-CA-16-001 LEVINSON, NICHOLAS MARK UNIVERSITY OF MINNESOTA A novel time-resolved fluorescence-based high-throughput screening technology for discovering allosteric kinase inhibitors Active
2020 R33 CA246455 RFA-CA-19-020 CHEN, FEI BROAD INSTITUTE, INC. Clinical implementations of spatial transcriptomics in tumors Active
2019 R21 CA236594 RFA-CA-18-002 GARBER, MANUEL UNIV OF MASSACHUSETTS MED SCH WORCESTER A modular; customizable sequencing system for simultaneous genotyping and transcript analysis in single cells Active
2018 R21 CA214239 RFA-CA-17-010 VAN DEVENTER, JAMES ALLEN TUFTS UNIVERSITY MEDFORD Discovering hybrid inhibitors for tumor microenvironment disruption Active
2017 R21 CA217751 RFA-CA-16-003 NECHAEV, SERGEI UNIVERSITY OF NORTH DAKOTA Transcriptome profiling of highly degraded specimens through global analysis of short RNA fragments. Active
2020 R33 CA246711 RFA-CA-19-020 FAN, RONG YALE UNIVERSITY High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer Active
2019 R21 CA236640 RFA-CA-18-002 BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories for targeting interstitial fluid pressure Active
2018 R33 CA223947 RFA-CA-17-011 BROWN, BRIAN D ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Pro-Codes: A novel vector and cell barcoding technology Active
2017 R21 CA217754 RFA-CA-16-001 DICKINSON, BRYAN UNIVERSITY OF CHICAGO rePPI-i: A system for the rapid continuous evolution of protein-protein interaction inhibitors Active
2020 R21 CA246359 RFA-CA-19-021 SEIBEL, ERIC J UNIVERSITY OF WASHINGTON Rapid Needle Biopsy Assessment at Point of Care to advance personalized cancer therapy Active
2019 R21 CA236685 RFA-CA-18-002 MANALIS, SCOTT R MASSACHUSETTS INSTITUTE OF TECHNOLOGY Building microenvironment-containing organoids from patient samples with single-cell precision Active
2018 R33 CA223581 RFA-CA-17-011 CHENG, JI-XIN BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) Quantitative SRS Imaging of Cancer Metabolism at Single Cell Level Active
2020 R33 CA247669 RFA-CA-19-022 HASHAM, MUNEER GULAMHUSEIN JACKSON LABORATORY Impact of Genetic Diversity on Human Xenograft Tumor Growth Active
2019 R21 CA236690 RFA-CA-18-002 KIM, HYUN JUNG UNIVERSITY OF TEXAS, AUSTIN A personalized colorectal cancer-on-a-chip for assessing tumor-microbiome crosstalk Active
2019 R21 CA240148 RFA-CA-18-002 ANGEL, PEGGY M MEDICAL UNIVERSITY OF SOUTH CAROLINA Enzymatic Tools for 2D Tissue Localized and Deeper Proteomic Sequencing of Cancer Stromal Proteins Active
2018 R33 CA223904 RFA-CA-17-011 CIMA, MICHAEL J MASSACHUSETTS INSTITUTE OF TECHNOLOGY Advanced development and validation of microdevices for high-throughput in situ drug sensitivity testing in tumors Active
2020 R43 CA243757 PAR-18-303 ERVIN, ERIC ELECTRONIC BIOSCIENCES, INC. N6-Methyl-2-O-Methyladenosine Sequencing Active
2019 R21 CA240162 RFA-CA-18-002 KEUNG, ALBERT NORTH CAROLINA STATE UNIVERSITY RALEIGH Intracellular CRISPR gRNA assembly for massively multiplexed; one pot; (epi)genetic screening Active
2018 R33 CA225539 RFA-CA-17-011 JIANG, NING UNIVERSITY OF TEXAS, AUSTIN An integrated therapeutic T cell receptor screening platform for adoptive cell therapy in cancer Active
2017 R33 CA204704 RFA-CA-16-002 WANG, YINGXIAO UNIVERSITY OF CALIFORNIA, SAN DIEGO Multiplex FRET Imaging of Kinase-Epigenome Interregulations in Live Cancer Cells Active
2020 R44 CA247353 PAR-18-303 FRIEDA, KIRSTEN SPATIAL GENOMICS, INC. Spatial and single cell analysis of tumor microenvironment by seqFISH+ Active
2019 R21 CA240199 RFA-CA-18-002 O'NEILL, RACHEL UNIVERSITY OF CONNECTICUT STORRS Development and Utilization of Splice-specific Antibodies Active
2018 R33 CA223908 RFA-CA-17-011 KONRY, TANIA TALI NORTHEASTERN UNIVERSITY Determining treatment sensitivity in B cell lymphoma by novel microfluidics-based NK cell immunogenicity platform Active
2017 R33 CA206907 RFA-CA-16-004 ISSADORE, DAVID AARON UNIVERSITY OF PENNSYLVANIA Rapid unbiased isolation and in situ RNA analysis of circulating tumor cells using a magnetic micropore-based diagnostic chip Active
2020 R43 CA250805 PAR-18-303 WANG, SHA VIVID TECHNOLOGIES New specific and rapid assay for in situ apoptosis labeling for cancer studies Active
2019 R21 CA240580 RFA-CA-18-002 MONTAGNA, CRISTINA ALBERT EINSTEIN COLLEGE OF MEDICINE Development of a high-resolution mapping platform for HPV DNA integration in premalignant lesions Active
2018 R33 CA225494 RFA-CA-17-011 LIU, YANG UNIVERSITY OF PITTSBURGH AT PITTSBURGH High-throughput super-resolution imaging of chromatin structures at different epigenetic states Active
2017 R33 CA206939 RFA-CA-16-004 PATTENDEN, SAMANTHA GAIL UNIV OF NORTH CAROLINA CHAPEL HILL The application of Enhanced Cavitation to enable DNA and Chromatin Extraction from Archived Tissues Active
2019 R33 CA225458 RFA-CA-18-003 KETTENBACH, ARMINJA NADINE DARTMOUTH COLLEGE Activity based profiling of Phosphoprotein phosphatases in cancer using mass spectrometry-based proteomics Active
2018 R33 CA225863 RFA-CA-17-011 LU, JUN YALE UNIVERSITY CRISPR-based Enhanced Molecular Chipper Technology for Identifying Functional Noncoding Elements in Cancer Active
2019 R33 CA225498 RFA-CA-18-003 CHEN, SIDI YALE UNIVERSITY Rapidly scalable platforms for direct in vivo screening of functional drivers in lethal cancers Active
2018 R33 CA222344 RFA-CA-17-011 SALIPANTE, STEPHEN J UNIVERSITY OF WASHINGTON Advanced development and validation of genome-scale molecular diagnostics for microsatelliteinstability using targeted molecular counting methods Active
2017 R33 CA212806 RFA-CA-16-004 ZILBERBERG, JENNY HACKENSACK UNIVERSITY MEDICAL CENTER Ex vivo culture platform validation for preservation of patient derived multiple myeloma cells Active
2019 R33 CA225549 RFA-CA-18-003 TAVANA, HOSSEIN UNIVERSITY OF AKRON A High Throughput Human Tumor Modeling Technology for Cancer Drug Discovery Active
2018 R33 CA228979 RFA-CA-17-011 SCHRUM, ADAM G UNIVERSITY OF MISSOURI-COLUMBIA Multiplex matrix ELISA for T cell protein-interaction networks in cancer Active
2019 R33 CA229042 RFA-CA-18-003 SCHNECK, JONATHAN P JOHNS HOPKINS UNIVERSITY A high-throughput nanoparticle assay to characterize cancer neoepitope-specific T cells Active
2018 R33 CA229023 RFA-CA-17-011 TEWARI, MUNEESH (contact); WALTER, NILS G UNIVERSITY OF MICHIGAN AT ANN ARBOR Optimization and Validation of Single-Molecule Kinetic Fingerprinting Technology for Rapid, Ultra-Specific Detection of Cancer Mutations Active
2019 R33 CA229068 RFA-CA-18-003 SCHIAVINATO EBERLIN, LIVIA UNIVERSITY OF TEXAS, AUSTIN Advanced Development of the MasSpec Pen for Cancer Diagnosis and Surgical Margin Evaluation Active
2018 R21 CA229037 RFA-CA-17-012 GULLEY, MARGARET L UNIV OF NORTH CAROLINA CHAPEL HILL EndoGenus Toolkit: A Biometric Method for Absolute Quantification of Tumor Markers by Massive Parallel Sequencing Active
2019 R33 CA235254 RFA-CA-18-003 FIOLKA, RETO PAUL UT SOUTHWESTERN MEDICAL CENTER Multiscale microscope for 3D cancer imaging in model organisms and organoids Active
2019 R33 CA235302 RFA-CA-18-003 DE VLAMINCK, IWIJN CORNELL UNIVERSITY Spatially Resolved Metagenomics to Explore Tumor-Microbiome Interactions in Human Colorectal Cancer Active
2018 R21 CA229027 RFA-CA-17-012 SKARDAL, ALEKSANDER (contact); STROWD, ROY ERVIN WAKE FOREST UNIVERSITY HEALTH SCIENCES Predicting Tumor Heterogeneity Evolution After Therapy In Patient-Derived Ex Vivo Glioblastoma Organoids Active
2017 R33 CA217652 RFA-CA-16-002 MAKRIGIORGOS, G. MIKE DANA-FARBER CANCER INST Maximum efficiency sequencing using nuclease-based mutation enrichment and digital barcodes Active

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