Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Year Award Type Project # RFA # PI/Project Leader Institution Title Statussort descending
2022 R21 RFA-CA-21-003 YAKOVLEV, VLADISLAV V TEXAS ENGINEERING EXPERIMENT STATION Molecular and cellular imaging of bone biopsies using AI augmented deep UV Raman microscopy Active
2022 R21 CA21-003 LIN, QIAO COLUMBIA UNIV NEW YORK MORNINGSIDE A Practical Approach to Tumor-Specific Aptamers for B-Cell Hematologic Malignancies Active
2021 R33 RFA-CA-20-018 HANSEN, ANDERS SEJR MASSACHUSETTS INSTITUTE OF TECHNOLOGY Super-resolution microscopy for dynamic analysis of focal enhancer amplifications in cancer Active
2022 R21 RFA-CA-21-003 SOPER, STEVEN ALLAN UNIVERSITY OF KANSAS LAWRENCE Molecular Sub-typing Breast Cancer Patients using a Liquid Biopsy Active
2022 R33 CA21-004 CHIU, BRIAN C-H UNIVERSITY OF CHICAGO A highly sensitive linear amplification based DNA methylation profiling technique for clinical cancer research Active
2021 R33 RFA-CA-20-018 LIU, XUEFENG OHIO STATE UNIVERSITY Validating Urine Derived Cancer Cells (UDCC) -- Non-Invasive and Living Liquid Biopsies -- in Bladder Cancer Clinics Active
2020 R21 RFA-CA-19-019 ALEXANDRAKIS, GEORGIOS UNIVERSITY OF TEXAS ARLINGTON Nanotechnology Enabled Selection Of MHC-peptide Ligands To Personalize Cancer Therapy Active
2023 R33 RFA-CA-22-002 LABAER, JOSHUA ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Multiplex In-Solution Protein Array (MISPA) for high throughput, quantitative, early profiling of pathogen-induced head and neck Active
2022 R21 CA21-003 BLAINEY, PAUL CLARK BROAD INSTITUTE, INC. Stitch-seq for genome-wide pooled genomic screening with RNA-seq readout Active
2020 R33 RFA-CA-19-020 MATRIX BHATNAGAR, PARIJAT SRI INTERNATIONAL T-cell Biofactories For Targeting Extracellular Matrix Active
2022 R21 RFA-CA-21-005 SHIBATA, DARRYL K UNIVERSITY OF SOUTHERN CALIFORNIA Photolithographic Tumor DNA Isolation Active
2022 R21 CA21-005 TANG, SINDY KAM-YAN STANFORD UNIVERSITY A micro-dissection platform for generating uniform-sized patient-derived tumor organoids (PDOs) for personalized cancer therapy Active
2021 R21 CA20-017 HOSHIKA, SHUICHI FOUNDATION FOR APPLIED MOLECULAR EVOLUTN High Quality Proteins with Multiple Post Translational Modifications Active
2020 R21 RFA-CA-19-021 GUPTA, GAUTAM UNIVERSITY OF LOUISVILLE Bio Cargos: Capture And Release Gels For Optimized Storage Of Cancer Biospecimens Active
2023 R61 RFA-CA-22-001 GAO, XIAOJING J STANFORD UNIVERSITY Program the Immune System against RAS-driven Cancer Active
2022 R21 RFA-CA-21-003 KNOWLES, DAVID ARTHUR NEW YORK GENOME CENTER A CRISPR/Cas13 approach for identifying individual transcript isoform function in cancer Active
2023 R33 RFA-CA-22-002 CUNNINGHAM, BRIAN T UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN Rapid, simple, and ultrasensitive quantitation of KRAS ctDNA at the point of care using CRISPR/Cas amplification and digital resolution biosensor microscopy Active
2023 R61 RFA-CA-22-001 SHAH, NEEL H COLUMBIA UNIV NEW YORK MORNINGSIDE A Generalizable Photo-Crosslinking Strategy to Identify Tyrosine Phosphatase Substrates Active
2023 R33 RFA-CA-22-002 JI, HANLEE P STANFORD UNIVERSITY Single cell modeling of cancer mutations Active
2023 R61 RFA-CA-22-001 DHAKAL, SOMA VIRGINIA COMMONWEALTH UNIVERSITY Single-Molecule High-Confidence Detection of miRNA Cancer Biomarkers Active
2023 R33 RFA-CA-22-002 MEYER, KATHRYN D DUKE UNIVERSITY A High-Throughput Screening Platform to Discover RNA Methylation Inhibitors Active
2021 R21 CA20-019 AKSAN, ALPTEKIN UNIVERSITY OF MINNESOTA Novel cryopreservation method for stabilization of manufactured therapeutic cells Active
2022 R33 RFA-CA-21-004 PAN, TAO UNIVERSITY OF CHICAGO Transfer RNA sequencing and application to cancer research and clinics Active
2022 R33 RFA-CA-21-004 WANG, TZA-HUEI JEFF JOHNS HOPKINS UNIVERSITY A low-cost, multiplexed digital high resolution melt platform for DNA methylation-based detection and identification of cancers in liquid biopsies Active
2021 R21 CA20-017 BHARGAVA, ROHIT UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN Spectroscopy Assisted Laser Microdissection Active
2020 R21 RFA-CA-19-019 LI, WEI TEXAS TECH UNIVERSITY Fractionation And Profiling Of Heterogeneous Circulating Tumor Cells Using A Hyperuniform- Structured Microchip Active
2023 R61 RFA-CA-22-001 LU, YUE UNIVERSITY OF UTAH Vesicle Epitope Transcript sequencing (VET-seq): Droplet-based Multiomic Profiling Platform for Single Vesicle Analysis Active
2022 R21 RFA-CA-21-005 TANG, SINDY KAM-YAN STANFORD UNIVERSITY A micro-dissection platform for generating uniform-sized patient-derived tumor organoids (PDOs) for personalized cancer therapy Active
2021 R33 CA20-018 ZENG, YONG UNIVERSITY OF FLORIDA Integrative Functional Profiling of Tumor-Derived Extracellular Vesicles Active
2020 R21 RFA-CA-19-019 LIANG, FU-SEN CASE WESTERN RESERVE UNIVERSITY Spatiotemporal Epitranscriptome Editing Technology Active
2021 R43 PAR-18-303 ALLEN, JEFFREY KEITH TUMORGEN, INC. Capture and Characterization of Highly Metastatic Cancer Cell Clusters in Transit from Lung Cancer Patient Whole Blood Specimens. Active
2023 R61 RFA-CA-22-001 PRATX, GUILLEM STANFORD UNIVERSITY A Novel Assay to Individualize Resensitization of Iodine-Refractory Thyroid Cancer Active
2021 R33 CA20-018 JIANG, NING JENNY UNIVERSITY OF PENNSYLVANIA A streamlined, high-throughput platform for validation of cancer antigen presentation and isolation of cancer antigen reactive T cells Active
2022 R21 RFA-CA-21-003 GIBBS, SUMMER LYNNE OREGON HEALTH & SCIENCE UNIVERSITY A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors Active
2021 R33 CA20-018 WEI, WEI INSTITUTE FOR SYSTEMS BIOLOGY Liquid biopsy-based toolkits for neoantigen and cognate TCR discovery for cancer immunotherapy Active
2023 R61 RFA-CA-22-001 CAMPAGNOLA, PAUL J UNIVERSITY OF WISCONSIN-MADISON A novel multimodal ECM analysis platform for tumor characterization combining morphological and spectrochemical tissue imaging approaches. Active
2021 R33 CA20-018 CHENG, JI-XIN BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy Active
2020 R21 RFA-CA-19-019 SHVETS, GENNADY CORNELL UNIVERSITY Phenotypic Assay For Drug Discovery And Personalized Medicine Based On Real-time Vibrational Spectroscopy Enhanced By Plasmonic Metasurfaces Active
2018 R43 PAR-18-303 LIM, MARK AMBERGEN, INC Highly Multiplexed Nanoscale Mass Spectrometric Imaging of Cancer Tissues Active
2023 R33 RFA-CA-22-004 DUNCAVAGE, ERIC J WASHINGTON UNIVERSITY A Rapid and Comprehensive Approach for Clinical Genomic Profiling in Lung Cancer Active
2020 R21 RFA-CA-19-019 TEWARI, MUNEESH UNIVERSITY OF MICHIGAN AT ANN ARBOR Highly Specific, Amplification-free, Single-molecule Counting Of Rare Methylated Dna Cancer Biomarkers Active
2022 R33 RFA-CA-21-004 NAEGLE, KRISTEN M UNIVERSITY OF VIRGINIA A synthetic toolkit for the recombinant production of tyrosine phosphorylated proteins and peptides Active
2021 R21 CA20-017 DIDENKO, VLADIMIR V BAYLOR COLLEGE OF MEDICINE In situ assay imaging nuclear RNA exosome activity for cancer studies Active
2020 R33 RFA-CA-19-020 WANG, SIYUAN YALE UNIVERSITY Multiplexed Imaging Of Chromatin Folding And Rna Profiles In Cancer Active
2000 R43 PAR-99-101 KOGON, ALEX A BIOLINX, LLC THOMSEN-FRIEDERICH ANTIGEN ASSAY FOR CANCER SCREENING Complete
2002 R43 PAR-01-105 HANNA, MICHELLE M RIBOMED BIOTECHNOLOGIES, INC. RAPID ANALYSIS OF CPG METHYLATION CHANGES IN CANCER Complete
2006 R33 RFA-CA-06-002 CLAWSON, GARY A. PENNSYLVANIA STATE UNIV HERSHEY MED CTR AN RNA SENSOR FOR DETECTION OF CIRCULATING TUMOR CELLS Complete
2009 R21 RFA-CA-08-006 SHAPIRO, BENJAMIN UNIV OF MARYLAND, COLLEGE PARK SPATIAL, HIGH-ACCURACY, MULTIPLEXED MAPPING OF GENES IN HUMAN TISSUE SECTIONS Complete
2013 R21 RFA-CA-12-002 SOPER, STEVEN ALLAN UNIV OF NORTH CAROLINA CHAPEL HILL ACUTE MYELOID LEUKEMIA: MRD ANALYSIS USING MODULAR UFLUIDICS AND UFLOW CYTOMETRY Complete
2016 R33 RFA-CA-15-003 BREUNIG, JOSHUA JOHN CEDARS-SINAI MEDICAL CENTER A GENETIC TOOLBOX FOR THE IDENTIFICATION AND INTERROGATION OF TUMOR CELLS OF ORIGIN, PROPAGATION, AND RECURRENCE FROM PATIENT-DERIVED ONCOGENIC DRIVERS Complete

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