Grants Awarded



Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.

New awards will be posted as they are issued.

Year Award Type Project # RFA # PI/Project Leader Institution Title Statussort ascending
2021 R21 CA20-019 AKSAN, ALPTEKIN UNIVERSITY OF MINNESOTA Novel cryopreservation method for stabilization of manufactured therapeutic cells Active
2020 R21 RFA-CA-19-019 LI, WEI TEXAS TECH UNIVERSITY Fractionation And Profiling Of Heterogeneous Circulating Tumor Cells Using A Hyperuniform- Structured Microchip Active
2022 R33 RFA-CA-21-004 PAN, TAO UNIVERSITY OF CHICAGO Transfer RNA sequencing and application to cancer research and clinics Active
2022 R33 RFA-CA-21-004 WANG, TZA-HUEI JEFF JOHNS HOPKINS UNIVERSITY A low-cost, multiplexed digital high resolution melt platform for DNA methylation-based detection and identification of cancers in liquid biopsies Active
2021 R21 CA20-017 BHARGAVA, ROHIT UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN Spectroscopy Assisted Laser Microdissection Active
2020 R21 RFA-CA-19-019 LIANG, FU-SEN CASE WESTERN RESERVE UNIVERSITY Spatiotemporal Epitranscriptome Editing Technology Active
2023 R61 RFA-CA-22-001 LU, YUE UNIVERSITY OF UTAH Vesicle Epitope Transcript sequencing (VET-seq): Droplet-based Multiomic Profiling Platform for Single Vesicle Analysis Active
2022 R21 RFA-CA-21-005 TANG, SINDY KAM-YAN STANFORD UNIVERSITY A micro-dissection platform for generating uniform-sized patient-derived tumor organoids (PDOs) for personalized cancer therapy Active
2021 R33 CA20-018 ZENG, YONG UNIVERSITY OF FLORIDA Integrative Functional Profiling of Tumor-Derived Extracellular Vesicles Active
2021 R43 PAR-18-303 ALLEN, JEFFREY KEITH TUMORGEN, INC. Capture and Characterization of Highly Metastatic Cancer Cell Clusters in Transit from Lung Cancer Patient Whole Blood Specimens. Active
2023 R61 RFA-CA-22-001 PRATX, GUILLEM STANFORD UNIVERSITY A Novel Assay to Individualize Resensitization of Iodine-Refractory Thyroid Cancer Active
2021 R33 CA20-018 JIANG, NING JENNY UNIVERSITY OF PENNSYLVANIA A streamlined, high-throughput platform for validation of cancer antigen presentation and isolation of cancer antigen reactive T cells Active
2022 R21 RFA-CA-21-003 GIBBS, SUMMER LYNNE OREGON HEALTH & SCIENCE UNIVERSITY A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors Active
2021 R33 CA20-018 WEI, WEI INSTITUTE FOR SYSTEMS BIOLOGY Liquid biopsy-based toolkits for neoantigen and cognate TCR discovery for cancer immunotherapy Active
2020 R21 RFA-CA-19-019 SHVETS, GENNADY CORNELL UNIVERSITY Phenotypic Assay For Drug Discovery And Personalized Medicine Based On Real-time Vibrational Spectroscopy Enhanced By Plasmonic Metasurfaces Active
2023 R61 RFA-CA-22-001 CAMPAGNOLA, PAUL J UNIVERSITY OF WISCONSIN-MADISON A novel multimodal ECM analysis platform for tumor characterization combining morphological and spectrochemical tissue imaging approaches. Active
2021 R33 CA20-018 CHENG, JI-XIN BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy Active
2020 R21 RFA-CA-19-019 TEWARI, MUNEESH UNIVERSITY OF MICHIGAN AT ANN ARBOR Highly Specific, Amplification-free, Single-molecule Counting Of Rare Methylated Dna Cancer Biomarkers Active
2018 R43 PAR-18-303 LIM, MARK AMBERGEN, INC Highly Multiplexed Nanoscale Mass Spectrometric Imaging of Cancer Tissues Active
2023 R33 RFA-CA-22-004 DUNCAVAGE, ERIC J WASHINGTON UNIVERSITY A Rapid and Comprehensive Approach for Clinical Genomic Profiling in Lung Cancer Active
2020 R33 RFA-CA-19-020 WANG, SIYUAN YALE UNIVERSITY Multiplexed Imaging Of Chromatin Folding And Rna Profiles In Cancer Active
2022 R33 RFA-CA-21-004 NAEGLE, KRISTEN M UNIVERSITY OF VIRGINIA A synthetic toolkit for the recombinant production of tyrosine phosphorylated proteins and peptides Active
2021 R21 CA20-017 DIDENKO, VLADIMIR V BAYLOR COLLEGE OF MEDICINE In situ assay imaging nuclear RNA exosome activity for cancer studies Active
2020 R43 PAR-18-303 WARREN, CHRISTOPHER L PROTEOVISTA, LLC Development Of The High Throughput Apt-snap Platform For Rapid Identification Ofnuclease-resistant Rna Aptamers Against P53 Missense Mutations Active
2023 R33 RFA-CA-22-002 WEISSLEDER MD PHD, RALPH MASSACHUSETTS GENERAL HOSPITAL Bioorthogonal probe development for highly parallel in vivo imaging Active
2021 R21 CA20-017 HAINER, SARAH JANE UNIVERSITY OF PITTSBURGH AT PITTSBURGH Using nanobodies to increase the sensitivity and resolution of chromatin profiling through uliCUT&RUN Active
2023 R33 RFA-CA-22-002 VAN GALEN, PETER BRIGHAM AND WOMEN'S HOSPITAL Clonal analysis of cancer by mitochondrial DNA barcoding Active
2021 R21 CA20-017 SCHULMAN, REBECCA JOHNS HOPKINS UNIVERSITY Secretion responsive Hydrogels for Identification of Functional single T cells (SHIFT) Active
2023 R33 RFA-CA-22-002 ISSADORE, DAVID AARON UNIVERSITY OF PENNSYLVANIA Combining Machine Learning and Nanofluidic Technology for The Multiplexed Diagnosis of Pancreatic Adenocarcinoma Active
2022 R21 CA21-003 SNYDER, JOSHUA CLAIR DUKE UNIVERSITY Mouse Paint: A massively combinatorial approach for illuminating tumor heterogeneity in True Color Active
2020 R33 RFA-CA-19-020 HALL, ADAM ROGER WAKE FOREST UNIVERSITY HEALTH SCIENCES Detecting diverse nucleic acid biomarkers of cancer with solid-state nanopores Active
2023 R33 RFA-CA-22-004 LEVENSON, RICHARD M UNIVERSITY OF CALIFORNIA AT DAVIS CoreView and FIBI for rapid-onsite evaluation and molecular profiling of core-needle breast biopsies. Active
2022 R21 CA21-005 BORGES, CHAD R ARIZONA STATE UNIVERSITY-TEMPE CAMPUS Aliquot-level visual indicators of biospecimen exposure to thawed conditions Active
2023 R61 RFA-CA-22-001 HACOHEN, NIR BROAD INSTITUTE, INC. Development of methods for highly multiplexed quantification of cancer proteomes using large-scale nanobody libraries Active
2022 R21 CA21-003 BOYLE, ALAN P UNIVERSITY OF MICHIGAN AT ANN ARBOR High-throughput inverted reporter assay for characterization of silencers and enhancer blockers Active
2021 R21 RFA-CA-20-019 SANTORE, MARIA M UNIVERSITY OF MASSACHUSETTS AMHERST Paper-based Breastmilk Collection System for Facile, In-Home Use Active
2022 R21 RFA-CA-21-003 SALIPANTE, STEPHEN J UNIVERSITY OF WASHINGTON Efficient, cost-effective, and ultrasensitive sequencing of somatic mutations Active
2022 R21 CA21-003 SCARCELLI, GIULIANO UNIV OF MARYLAND, COLLEGE PARK Stimulated Brillouin Flow Cytometry for biomechanical assessment of metastatic potential Active
2021 R21 RFA-CA-20-017 WILSON, GERALD M UNIVERSITY OF MARYLAND BALTIMORE Suppressing oncogenic RNA regulons using engineered zinc finger ribonucleases Active
2023 R33 RFA-CA-22-002 MURETTA, JOSEPH M UNIVERSITY OF MINNESOTA Engineering Protein Modulators of Notch Activation for T-cell immunotherapy Active
2022 R33 CA21-004 NORMAN, THOMAS MAXWELL SLOAN-KETTERING INST CAN RESEARCH Systematic characterization of cancer variants using single-cell functional genomics Active
2021 R21 RFA-CA-20-017 ZHANG, FANGLIANG UNIVERSITY OF MIAMI SCHOOL OF MEDICINE Targeted degradation of proteins by affinity peptide conjugated ubiquitin (APCU) Active
2022 R21 RFA-CA-21-003 NABA, ALEXANDRA UNIVERSITY OF ILLINOIS AT CHICAGO Enhanced mass-spectrometry-based approaches for in-depth profiling of the cancer extracellular matrix Active
2022 R21 CA21-003 LEE, HAKHO MASSACHUSETTS GENERAL HOSPITAL 3D Fourier Imaging System for High Throughput Analyses of Cancer Organoids Active
2021 R21 RFA-CA-20-017 STILL, AMANDA NICOLE HAYMOND GEORGE MASON UNIVERSITY New Hybrid Molecular Modalities Comprised of DNA-Origami and Interfering Peptides as Inhibitors of Protein-Protein Interactions Active
2022 R33 RFA-CA-21-004 LANDAU, DAN WEILL MEDICAL COLL OF CORNELL UNIV Expanding the GoT toolkit to link single-cell clonal genotypes with protein, transcriptomic, epigenomic and spatial phenotypes Active
2022 R21 CA21-003 BELCHER, ANGELA M MASSACHUSETTS INSTITUTE OF TECHNOLOGY A cell-cycle induced genetic recorder for simultaneous recovery of cell divisions and lineage Active
2021 R21 RFA-CA-20-017 XIAO, HAN RICE UNIVERSITY Development of Bone-Targeting Antibodies for Ewing Sarcoma Using Genetic Code Expansion Active
2023 R61 RFA-CA-22-001 YAN, HAO ARIZONA STATE UNIVERSITY-TEMPE CAMPUS High-throughput, purification-free, and ultrasensitive transmembrane nanosensor arrays for digital counting of microRNA biomarkers of intact exosomes Active
2022 R33 CA21-004 DRAKE, RICHARD R MEDICAL UNIVERSITY OF SOUTH CAROLINA Targeted Isolation and Identification of Sialylated Glycoproteins in Cancer Tissues, Cells and Biofluids Active

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