Grants Awarded
Click on any project title for a more detailed description of the project. For more information about any of these awards (e.g., PI contact information or associated publications), please use the corresponding project number to search for information at the NIH Reporter website. Consistent with NIH policy, abstracts are not available for projects receiving their first award within the past year, so descriptions provided below are from the NCI program director.
New awards will be posted as they are issued.
Year | Award Type | Project # | RFA # | PI/Project Leader | Institution | Title | Status |
---|---|---|---|---|---|---|---|
2022 | R21 | CA269103 | CA21-003 | BLAINEY, PAUL CLARK | BROAD INSTITUTE, INC. | Stitch-seq for genome-wide pooled genomic screening with RNA-seq readout | Active |
2022 | R33 | CA269100 | CA21-004 | CHIU, BRIAN C-H | UNIVERSITY OF CHICAGO | A highly sensitive linear amplification based DNA methylation profiling technique for clinical cancer research | Active |
2022 | R21 | CA269099 | CA21-003 | YAKOVLEV, VLADISLAV V | TEXAS ENGINEERING EXPERIMENT STATION | Molecular and cellular imaging of bone biopsies using AI augmented deep UV Raman microscopy | Active |
2022 | R21 | CA261775 | CA21-003 | LIN, QIAO | COLUMBIA UNIV NEW YORK MORNINGSIDE | A Practical Approach to Tumor-Specific Aptamers for B-Cell Hematologic Malignancies | Active |
2022 | R33 | CA269094 | CA21-004 | MOELLERING, RAYMOND E | UNIVERSITY OF CHICAGO | Single-Cell Protein Activity Profiling in Breast Cancer Cells and Tissues | Active |
2022 | R21 | CA269091 | CA21-005 | BORGES, CHAD R | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS | Plate reader assays to forensically assess exposure of plasma and serum to thawed conditions | Active |
2022 | R33 | CA258012 | CA21-004 | KARGINOV, ANDREI V | UNIVERSITY OF ILLINOIS AT CHICAGO | Optogenetic Control of Tumor Initiation and Tumor Progression in vivo | Active |
2022 | R33 | CA269015 | CA21-004 | ADEY, ANDREW | OREGON HEALTH & SCIENCE UNIVERSITY | Accessible high-throughput single-cell genome sequencing | Active |
2022 | R33 | CA261696 | CA21-004 | MERAJVER, SOFIA DIANA | UNIVERSITY OF MICHIGAN AT ANN ARBOR | Advanced development and validation of an in vitro platform to phenotype brain metastatic tumor cells using artificial intelligence | Active |
2022 | R21 | CA257816 | CA21-003 | COUNTER, CHRISTOPHER M | DUKE UNIVERSITY | Adapting K-MDS to detect KRAS-mutant ctDNA | Active |
2022 | R21 | CA267260 | CA21-003 | ARMITAGE, BRUCE A | CARNEGIE-MELLON UNIVERSITY | Fluorescent gammaPNA Miniprobes for Imaging Telomeric RNA | Active |
2022 | R33 | CA267226 | CA21-004 | DRAKE, RICHARD R | MEDICAL UNIVERSITY OF SOUTH CAROLINA | Targeted Isolation and Identification of Sialylated Glycoproteins in Cancer Tissues, Cells and Biofluids | Active |
2022 | R21 | CA257980 | CA21-003 | BELCHER, ANGELA M | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | A cell-cycle induced genetic recorder for simultaneous recovery of cell divisions and lineage | Active |
2022 | R21 | CA267222 | CA21-003 | LEE, HAKHO | MASSACHUSETTS GENERAL HOSPITAL | 3D Fourier Imaging System for High Throughput Analyses of Cancer Organoids | Active |
2022 | R33 | CA267221 | CA21-004 | NORMAN, THOMAS MAXWELL | SLOAN-KETTERING INST CAN RESEARCH | Systematic characterization of cancer variants using single-cell functional genomics | Active |
2022 | R21 | CA258008 | CA21-003 | SCARCELLI, GIULIANO | UNIV OF MARYLAND, COLLEGE PARK | Stimulated Brillouin Flow Cytometry for biomechanical assessment of metastatic potential | Active |
2022 | R21 | CA257864 | CA21-003 | BOYLE, ALAN P | UNIVERSITY OF MICHIGAN AT ANN ARBOR | High-throughput inverted reporter assay for characterization of silencers and enhancer blockers | Active |
2022 | R21 | CA250999 | CA21-005 | BORGES, CHAD R | ARIZONA STATE UNIVERSITY-TEMPE CAMPUS | Aliquot-level visual indicators of biospecimen exposure to thawed conditions | Active |
2022 | R21 | CA257942 | CA21-003 | GIBBS, SUMMER LYNNE | OREGON HEALTH & SCIENCE UNIVERSITY | A Novel Fluorescence Imaging Platform to Predict Response to Combinatorial Tyrosine Kinase Inhibitors | Active |
2022 | R21 | CA267012 | CA21-003 | SNYDER, JOSHUA CLAIR | DUKE UNIVERSITY | Mouse Paint: A massively combinatorial approach for illuminating tumor heterogeneity in True Color | Active |
2021 | R21 | CA263147 | CA20-017 | BHARGAVA, ROHIT | UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN | Spectroscopy Assisted Laser Microdissection | Active |
2021 | R21 | CA256084 | CA20-017 | DI CARLO, DINO | UNIVERSITY OF CALIFORNIA LOS ANGELES | Lab on a particle technology for functional screening of therapeutic cells | Complete |
2021 | R21 | CA251027 | CA20-017 | SCHULMAN, REBECCA | JOHNS HOPKINS UNIVERSITY | Secretion responsive Hydrogels for Identification of Functional single T cells (SHIFT) | Active |
2021 | R21 | CA256128 | CA20-017 | DEININGER, MICHAEL W | VERSITI WISCONSIN, INC. | A Bioluminescent Assay for Direct Measurement of Sirtuin Activity in Cancer Cells | NCE |
2021 | R21 | CA261737 | CA20-017 | HAINER, SARAH JANE | UNIVERSITY OF PITTSBURGH AT PITTSBURGH | Using nanobodies to increase the sensitivity and resolution of chromatin profiling through uliCUT&RUN | Active |
2021 | R21 | CA261734 | CA20-019 | AKSAN, ALPTEKIN | UNIVERSITY OF MINNESOTA | Novel cryopreservation method for stabilization of manufactured therapeutic cells | Active |
2021 | R33 | CA256112 | CA20-018 | WEI, WEI | INSTITUTE FOR SYSTEMS BIOLOGY | Liquid biopsy-based toolkits for neoantigen and cognate TCR discovery for cancer immunotherapy | Active |
2021 | R33 | CA256086 | CA20-018 | JIANG, NING JENNY | UNIVERSITY OF PENNSYLVANIA | A streamlined, high-throughput platform for validation of cancer antigen presentation and isolation of cancer antigen reactive T cells | Active |
2021 | R33 | CA261726 | CA20-018 | CHENG, JI-XIN | BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) | Mapping Cancer Metabolism by Mid-infrared Photothermal Microscopy | Active |
2021 | R21 | CA255979 | CA20-017 | DIDENKO, VLADIMIR V | BAYLOR COLLEGE OF MEDICINE | In situ assay imaging nuclear RNA exosome activity for cancer studies | Active |
2021 | R43 | CA261362 | PAR-18-303 | ALLEN, JEFFREY KEITH | TUMORGEN, INC. | Capture and Characterization of Highly Metastatic Cancer Cell Clusters in Transit from Lung Cancer Patient Whole Blood Specimens. | Active |
2021 | R33 | CA252158 | CA20-018 | ZENG, YONG | UNIVERSITY OF FLORIDA | Integrative Functional Profiling of Tumor-Derived Extracellular Vesicles | Active |
2021 | R21 | CA236686 | CA20-017 | FARIS, GREGORY W | NUMENTUS TECHNOLOGIES INC. | Decoding Individual Exosomes in Cancer | NCE |
2021 | R21 | CA258013 | CA20-019 | NAUTIYAL, SHIVANI | PRIME GENOMICS, INC. | Device for Preservation of Cell Free RNA in Saliva | NCE |
2020 | R21 | CA240214 | RFA-CA-19-019 | CICERONE, MARCUS T | GEORGIA INSTITUTE OF TECHNOLOGY | Label-Free Cell-Resolved Metabolomics for Tumor Microscopy | Complete |
2020 | R33 | CA240181 | RFA-CA-19-020 | COOKS, ROBERT GRAHAM | PURDUE UNIVERSITY | Advanced Development of Desorption Electrospray Ionization Mass Spectrometry for Intraoperative Molecular Diagnosis of Brain Cancer using Pathology Biopsies | Complete |
2020 | R33 | CA240191 | RFA-CA-19-020 | RECHT, MICHAEL | PALO ALTO RESEARCH CENTER | High-Throughput Screening Platform for Cancer Drug Discovery | Active |
2020 | R21 | CA247671 | RFA-CA-19-019 | MARTO, JARROD A | DANA-FARBER CANCER INST | Tools for DUB Drug Discovery | Complete |
2020 | R33 | CA247669 | RFA-CA-19-022 | HASHAM, MUNEER GULAMHUSEIN | JACKSON LABORATORY | Impact of Genetic Diversity on Human Xenograft Tumor Growth | Complete |
2020 | R44 | CA247353 | PAR-18-303 | FRIEDA, KIRSTEN | SPATIAL GENOMICS, INC. | Spatial and single cell analysis of tumor microenvironment by seqFISH+ | Complete |
2020 | R33 | CA246711 | RFA-CA-19-020 | FAN, RONG | YALE UNIVERSITY | High-throughput single-cell co-sequencing of small and large RNAs to identify molecular circuitry in cancer | Complete |
2020 | R21 | CA236653 | RFA-CA-19-019 | ISSADORE, DAVID AARON | UNIVERSITY OF PENNSYLVANIA | High Throughput Digital Droplet ELISA for Ultrasensitive Multiplexed Diagnostics | NCE |
2020 | R33 | CA246455 | RFA-CA-19-020 | CHEN, FEI | BROAD INSTITUTE, INC. | Clinical implementations of spatial transcriptomics in tumors | Complete |
2020 | R21 | CA229024 | RFA-CA-19-019 | HUR, SOOJUNG CLAIRE | JOHNS HOPKINS UNIVERSITY | Development of a microfluidic primary cell editing platform (pCEP) for personal gene therapy | Complete |
2020 | R33 | CA246363 | RFA-CA-19-020 | LEVINSON, NICHOLAS MARK | UNIVERSITY OF MINNESOTA | Time-resolved FRET-based allostery sensors for any protein kinase drug target | NCE |
2020 | R21 | CA246359 | RFA-CA-19-021 | SEIBEL, ERIC J | UNIVERSITY OF WASHINGTON | Rapid Needle Biopsy Assessment at Point of Care to advance personalized cancer therapy | Complete |
2020 | R21 | CA246358 | RFA-CA-19-019 | SEELIG, GEORG | UNIVERSITY OF WASHINGTON | High-resolution spatial transcriptomics through light patterning | Complete |
2020 | R21 | CA236612 | RFA-CA-19-019 | REVZIN, ALEXANDER | MAYO CLINIC ROCHESTER | A microfluidic cell culture platform for personalizing pancreatic cancer therapies | NCE |
2019 | R33 | CA235319 | RFA-CA-18-003 | YANG, JENNY J. | GEORGIA STATE UNIVERSITY | Multi-color Mapping of Cancer Molecular Signatures and Tumor microenvironment | Complete |
2019 | R33 | CA229068 | RFA-CA-18-003 | SCHIAVINATO EBERLIN, LIVIA | UNIVERSITY OF TEXAS, AUSTIN | Advanced Development of the MasSpec Pen for Cancer Diagnosis and Surgical Margin Evaluation | Complete |