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Novel platform linking cancer-specific glycosylation with cell signaling outcomes


Year of Award:
2018
Status:
Active
Award Type:
R21
Project Number:
CA229044
RFA Number:
RFA-CA-17-010
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
ABBOTT, KAREN L
Institution:
UNIV OF ARKANSAS FOR MED SCIS
ABSTRACT Abnormal glycosylation is a hallmark of many cancers that contributes to tumor growth and invasion. There are many protein receptors that are regulated abnormally in cancer due to mutations and/or alterations in glycosylation. Studies to link spe