Novel NeuCode Tagging Reagents for Identification and Quantification of Intact Proteoforms in Cancer Tissues


Year of Award:
2018
Award Type:
R21
Project Number:
1R21CA223887-01
RFA Number:
RFA-CA-17-010
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
SMITH, LLOYD M
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF WISCONSIN-MADISON
In this proposal we address a very substantial limitation in the ability of existing technologies toprovide critical proteomic information from normal and cancer tissues. In standard proteomicanalyses, proteins in complex protein mixtures such as total ce