Year of Award:
2018
Status:
NCE
Award Type:
R33
Project Number:
CA222344
RFA Number:
RFA-CA-17-011
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
SALIPANTE, STEPHEN J
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF WASHINGTON
External Link:
https://projectreporter.nih.gov/project_info_description.cfm?aid=9432343
Microsatellite Instability (MSI), the spontaneous loss or gain of nucleotides from repetitive DNA tracts, is amolecular phenotype in oncology that is associated with genomic hypermutability and mutations in DNA repairenzymes. Although originally described