Rapid unbiased isolation and in situ RNA analysis of circulating tumor cells using a magnetic micropore-based diagnostic chip


Year of Award:
2017
Status:
Complete
Award Type:
R33
Project Number:
CA206907
RFA Number:
RFA-CA-16-004
Technology Track:
Biospecimen Science Technologies
PI/Project Leader:
ISSADORE, DAVID AARON
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF PENNSYLVANIA

Pancreatic cancer is the fourth most common cause of cancer related death in the UnitedStates, with a five year survival rate of only 4%. We have recently shown that circulatingpancreatic cells (CPCs) can be detected in the blood at the onset of the disea