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High Content Screening of Multicellular Invasion with 3D Traction Force Microscopy


Year of Award:
2017
Status:
Complete
Award Type:
R21
Project Number:
CA212932
RFA Number:
RFA-CA-16-001
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
WONG, IAN Y
Other PI or Project Leader:
N/A
Institution:
BROWN UNIVERSITY
Malignant carcinomas disseminate individual cells and multicellular clusters through coordinated processes ofcellular detachment and motility. These mechanical cell-cell and cell-matrix interactions can varyheterogeneously across different cells and also