Development and validation of nanoparticle-mediated microfluidic profiling approach for rare cell analysis


Year of Award:
2017
Status:
Complete
Award Type:
R33
Project Number:
CA204574
RFA Number:
RFA-CA-16-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
KELLEY, SHANA O
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF TORONTO

Circulating tumour cells (CTC) are shed into the vasculature from primary tumours, and have been shown tocontribute to the formation of metastatic lesions in model systems. Monitoring these circulating cells thereforepresents, in principle, a means to mon