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Protein painting identifies therapeutic targets at protein-protein interfaces


Year of Award:
2016
Status:
Complete
Award Type:
R33
Project Number:
CA206937
RFA Number:
RFA-CA-15-003
Technology Track:
Biospecimen Science Technologies
PI/Project Leader:
LIOTTA, LANCE ALLEN
Other PI or Project Leader:
N/A
Institution:
GEORGE MASON UNIVERSITY

The next generation of molecular cancer therapeutics will target pivotal protein-protein interaction interfacesparticipating in immune cell receptor signaling, oncogenes, and suppressor genes. We will implement a trulytransformative, wholly novel, technol