GESI: a novel technology for functional imaging in living cells


Year of Award:
2016
Award Type:
R33
Project Number:
1R33CA196445-01A1
RFA Number:
RFA-CA-15-003
Technology Track:
Biospecimen Science Technologies
PI/Project Leader:
LAM, KIT S
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF CALIFORNIA AT DAVIS
The Genetically Encoded Small Illuminant (GESI) technology proposed here consists of using an one-bead-one-compound (OBOC) combinatorial library screen to identify short peptide(s) that activate fluorophores/dyes,which can be coupled to alterations of the