MOLECULAR ANALYSIS OF PHYSICAL MICROENVIRONMENTAL CONTROL OF TUMOR CELL INVASION


Year of Award:
2014
Award Type:
R21
Project Number:
CA174573
RFA Number:
RFA-CA-13-001
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
KUMAR, SANJAY
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF CALIFORNIA BERKELEY
Tumor invasion and metastasis are strongly regulated by biophysical interactions between tumor cells and the extracellular matrix (ECM). While the influence of ECM stiffness on cell migration, adhesion, and contractility has been extensively studied in tw