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INTEGRATING MASS CYTOMETRIC AND TRANSCRIPTOMIC PROFILES OF SOLID TUMORS


Year of Award:
2014
Status:
Complete
Award Type:
R33
Project Number:
CA183692
RFA Number:
RFA-CA-13-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
WEISS, WILLIAM A
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
As tumors grow and evolve, tumor, stromal, and immune cells change, displaying new and variable phenotypes as a result of both genetic and non-genetic influences. This intratumoral phenotypic heterogeneity is an important consideration for cancer therapy,