DIGITAL DETECTION OF TUMOR-DERIVED CIRCULATING METHYLATED DNA


Year of Award:
2014
Award Type:
R21
Project Number:
CA186809
RFA Number:
RFA-CA-13-001
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
WANG, TZA-HUEI
Other PI or Project Leader:
N/A
Institution:
JOHNS HOPKINS UNIVERSITY
Aberrantly methylated DNA is found abundantly in all forms of cancer and the tumors that produce them. In fact, it has been estimated that within the cells of every tumor are several hundreds of aberrantly methylated CpG islands, many of which are promote