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NEW REAGENTS FOR TRACKING PROTEIN OXIDATION IN CELLS BY MS AND IMAGING METHODS


Year of Award:
2013
Status:
Complete
Award Type:
R33
Project Number:
CA177461
RFA Number:
RFA-CA-12-003
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
FURDUI, CRISTINA MARIA
Other PI or Project Leader:
POOLE, LESLIE B.
Institution:
WAKE FOREST UNIVERSITY HEALTH SCIENCES
The association of reactive oxygen species (ROS) with the initiation and progression of cancer, including stimulation of tumor growth and metastasis, is well established; paradoxically, ROS are also important players in many anti-cancer treatments involvi