HIGH-THROUGHPUT, MULTIPLEXED DETECTION OF MIRNA BIOMARKERS IN SINGLE CANCER CELLS


Year of Award:
2013
Award Type:
R21
Project Number:
CA177393
RFA Number:
RFA-CA-12-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
FAN, RONG
Other PI or Project Leader:
DOYLE, PATRICK S
Institution:
YALE UNIVERSITY
MicroRNAs (miRNAs) are a class of small non-coding RNAs recently discovered as negative gene regulators. A large faction of miRNAs are located within the fragile regions of chromosomes, which are areas of the genome more tightly associated with human canc