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PCR-FREE MULTIPLEXED DETECTION OF CIRCULATING MIRNA IN BLOOD


Year of Award:
2012
Status:
Complete
Award Type:
R21
Project Number:
CA173390
RFA Number:
RFA-CA-12-002
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
WANG, TZA-HUEI
Other PI or Project Leader:
N/A
Institution:
JOHNS HOPKINS UNIVERSITY
Micro RNAs (miRNAs) are short nucleotides (~ 20 nt) that act as regulators of gene expression in nearly all cellular processes including differentiatio, proliferation, and apoptosis. In tumors, miRNAs have been shown to play key roles in cancer processes