TARGETING CANCER CELLS WITH FUNCTIONALIZED NANOPARTICLE LIBRARIES


Year of Award:
2011
Award Type:
R21
Project Number:
CA157366
RFA Number:
RFA-CA-10-005
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
LEVY, MATTHEW
Other PI or Project Leader:
N/A
Institution:
ALBERT EINSTEIN COLLEGE OF MEDICINE
We propose to use a combination of two powerful techniques: aptamer selection (systematic evolution of ligands by exponential enrichment; SELEX) and in vitro compartmentalization (IVC), to develop a new method of generating libraries of functionalized nan