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HIGHLY PARALLEL EDMAN SEQUENCING OF INDIVIDUAL PEPTIDE MOLECULES


Year of Award:
2010
Status:
Complete
Award Type:
R21
Project Number:
CA151197
RFA Number:
RFA-CA-09-008
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
MITRA, ROBI D
Other PI or Project Leader:
N/A
Institution:
WASHINGTON UNIVERSITY
Most biological processes are executed by proteins, but no method currently exists to accurately measure protein abundance and post-translational state proteome-wide. To redress this deficiency, we propose Digital Analysis of Proteins by End Sequencing (D