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OXMRM: A TECHNIQUE TO QUANTIFY OXIDATION OF ENDOGENOUS REDOX-SENSITIVE CYSTEINES


Year of Award:
2009
Status:
Complete
Award Type:
R21
Project Number:
CA138308
RFA Number:
RFA-CA-08-006
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
HELD, JASON M.
Other PI or Project Leader:
N/A
Institution:
BUCK INSTITUTE FOR RESEARCH ON AGING
Thiol signaling by reactive nitrogen and oxygen species (RN/OS) regulates aspects of tumor growth, migration, invasion, survival, angiogenesis, and metastasis; however the key modifications and mechanisms of thiol signaling in cancer are relatively obscur