OPTIMIZING MSNP FOR PROFILING DNA METHYLATION IN CANCERS AND PRECURSOR LESIONS


Year of Award:
2009
Award Type:
R21
Project Number:
CA125461
RFA Number:
RFA-CA-08-007
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
TYCKO, BENJAMIN
Other PI or Project Leader:
N/A
Institution:
COLUMBIA UNIVERSITY HEALTH SCIENCES
Alterations in DNA methylation are hallmarks of cancer cells, and epigenetic markers are increasingly viewed as having great potential for diagnosing, classifying and prognosticating cancers and cancer precursor lesions. Thus, a technical challenge is to