MASSIVELY PARALLEL SEQUENCING TECHNOLOGY FOR CANCER EPIGENOME.


Year of Award:
2009
Award Type:
R21
Project Number:
CA137689
RFA Number:
RFA-CA-08-007
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
SHEN, LANLAN
Other PI or Project Leader:
N/A
Institution:
UNIVERSITY OF TX MD ANDERSON CAN CTR
Methylated CpG island amplification (MCA) is a DNA library construction technique that permits amplification of 146,148 methylated CpG rich regions throughout the whole genome, covering 76% of all genes and 70% of all bona fide CpG islands. When coupled w