Year of Award:
Molecular & Cellular Analysis Technologies
KEELY, PATRICIA J
Other PI or Project Leader:
UNIVERSITY OF WISCONSIN-MADISON
Mammary epithelial cells undergo ductal morphogenesis only in compliant 3D extracellular matrices (floating collagen gels or Matrigel), but not in otherwise identical matrices that are stiff (attached 3D collagen gels) or have increased collagen density.