PROTEOMIC PROFILING OF CANCER-RELATED REDOX SIGNALING PATHWAYS


Year of Award:
2008
Award Type:
R33
Project Number:
CA126659
RFA Number:
RFA-CA-07-034
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
POOLE, LESLIE B.
Other PI or Project Leader:
N/A
Institution:
WAKE FOREST UNIVERSITY HEALTH SCIENCES
It is widely appreciated that reactive oxygen species (ROS) play a major role in the initiation of cancer, and they are also implicated in many cancer therapies, such as ionizing radiation, cisplatin and taxanes. More recently, it has been discovered that