MASS SPECTROMETRY METHODS FOR PROBING METABOLIC DYNAMICS IN NORMAL & CANCER CELLS


Year of Award:
2008
Award Type:
R21
Project Number:
CA128620
RFA Number:
RFA-CA-07-035
Technology Track:
Molecular & Cellular Analysis Technologies
PI/Project Leader:
RABINOWITZ, JOSHUA D
Other PI or Project Leader:
N/A
Institution:
PRINCETON UNIVERSITY
Many of the most clinically important chemotherapeutic agents inhibit the metabolism of tumor cells. Our overarching goal is to develop a complete and quantitative understanding of the metabolic differences between normal and cancer cells, and to use this